Evidence map›Paper›PMID 32417380›Full record

ArticleJournal of cardiac failure2020

Coronavirus Disease-2019 in Heart Transplant Recipients in Southeastern Michigan: A Case Series.

Scott W Ketcham, Sarah K Adie, Ashley Malliett, Ahmad A Abdul-Aziz, Abbas Bitar, Gillian Grafton, Matthew C Konerman

Open access · bronzeAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of cardiac failure, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers, 8 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
30citing papers in PubMed, 8 pooled it
1.0field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

30 citing papers in PubMed, 8 syntheses or guidelines pooled it, 43 citations in OpenAlex.

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  8. COVID-19 clinical manifestations and treatment strategies among solid-organ recipients: A systematic review of cases.Transplant infectious disease : an official journal of the Transplantation Society · 2020
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Scott W KetchamDepartment of Internal Medicine, University of Michigan, Ann Arbor, Michigan. Electronic address: ketchams@med.umich.edu.
Sarah K AdieDepartment of Pharmacy, University of Michigan, Ann Arbor, Michigan.
Ashley MalliettDivision of Cardiology, Department of Internal Medicine, Henry Ford Health System, Detroit, Michigan.
Ahmad A Abdul-AzizDivision of Cardiology, Department of Internal Medicine, University of Michigan, Ann Arbor, Michigan.
Abbas BitarDivision of Cardiology, Department of Internal Medicine, University of Michigan, Ann Arbor, Michigan.
Gillian GraftonDivision of Cardiology, Department of Internal Medicine, Henry Ford Health System, Detroit, Michigan.
Matthew C KonermanDivision of Cardiology, Department of Internal Medicine, University of Michigan, Ann Arbor, Michigan.
University of Michigan–Ann Arbor · USHenry Ford Health System · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundSince coronavirus disease 2019 (COVID-19) was first identified in Wuhan, China, in December 2019, the number of cases has risen exponentially. Clinical characteristics and outcomes among patients with orthotopic heart transplant (OHT) with COVID-19 remain poorly described.

methodsWe performed a retrospective case series of patients with OHT with COVID-19 admitted to 1 of 2 hospitals in Southeastern Michigan between March 21 and April 22, 2020. Clinical data were obtained through review of the electronic medical record. Final date of follow-up was May 7, 2020. Demographic, clinical, laboratory, radiologic, treatment, and mortality data were collected and analyzed.

resultsWe identified 13 patients with OHT admitted with COVID-19. The mean age of patients was 61 ± 12 years, 100% were black males, and symptoms began 6 ± 4 days before admission. The most common symptoms included subjective fever (92%), shortness of breath (85%), and cough (77%). Six patients (46%) required admission to the intensive care unit. Two patients (15%) died during hospitalization.

conclusionsBlack men may be at increased risk for COVID-19 among patients with OHT. Presenting signs and symptoms in this cohort are similar to those in the general population. Elevated inflammatory markers on presentation appear to be associated with more severe illness.

Indexed as

BetacoronavirusHeart TransplantationAdultAgedCohort StudiesCoronavirus InfectionsCOVID-19Critical CareFemaleHeart FailureHospitalizationHumansMaleMichiganMiddle AgedPandemicsAdvanced heart failureCOVIDheart transplantimmunosuppression

Identifiers

PMID32417380
PMCPMC7224667
OpenAlexW3024259740

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.