Evidence map›Paper›PMID 32416733›Full record

ArticleParasites & vectors2020

Effects of larval exposure to sublethal doses of Bacillus thuringiensis var. israelensis on body size, oviposition and survival of adult Anopheles coluzzii mosquitoes.

Steven Gowelo, James Chirombo, Jeroen Spitzen, Constantianus J M Koenraadt, Themba Mzilahowa, Henk van den Berg, Willem Takken, Robert McCann

Open access · goldAbstract read
In one paragraph

Article in Parasites & vectors, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.2field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 24 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 4 countries.

Steven GoweloLaboratory of Entomology, Wageningen University & Research, Wageningen, The Netherlands. gowellsteve@gmail.com.
James ChiromboMalawi-Liverpool-Wellcome Trust Clinical Research Programme, Blantyre, Malawi.
Jeroen SpitzenLaboratory of Entomology, Wageningen University & Research, Wageningen, The Netherlands.
Constantianus J M KoenraadtLaboratory of Entomology, Wageningen University & Research, Wageningen, The Netherlands.
Themba MzilahowaMalaria Alert Centre, College of Medicine, Blantyre, Malawi.
Henk van den BergLaboratory of Entomology, Wageningen University & Research, Wageningen, The Netherlands.
Willem TakkenLaboratory of Entomology, Wageningen University & Research, Wageningen, The Netherlands.
Robert McCannLaboratory of Entomology, Wageningen University & Research, Wageningen, The Netherlands.
Wageningen University & Research · NLUniversity of Liverpool · GBUniversity of Maryland, Baltimore · US

Funding

FELLOWSHIP TRAINING PROGRAM IN VACCINOLOGYT32AI007524 · NIAID · UNIVERSITY OF MARYLAND BALTIMORE · PI Marcelo B. Sztein · 1997 to 2026
$6.4M
6 · The paper itself

Abstract

backgroundApplication of the larvicide Bacillus thuringiensis var. israelensis (Bti) is a viable complementary strategy for malaria control. Efficacy of Bti is dose-dependent. There is a knowledge gap on the effects of larval exposure to sublethal Bti doses on emerging adult mosquitoes. The present study examined the effect of larval exposure to sublethal doses of Bti on the survival, body size and oviposition rate in adult Anopheles coluzzii.

methodsThird-instar An. coluzzii larvae were exposed to control and sublethal Bti concentrations at LC

resultsExposure to LC

conclusionsExposure of An. coluzzii larvae to sublethal Bti doses reduces longevity of resultant adults and is associated with larger adult size and unclear effect on oviposition. These findings suggest that anopheline larval exposure to sublethal Bti doses, though not recommended, could reduce vectorial capacity for malaria vector populations by increasing mortality of resultant adults.

Indexed as

Body SizeLongevityOvipositionAnimalsAnophelesBacillus thuringiensisFemaleLarvaMaleMosquito ControlMosquito VectorsPest Control, BiologicalBacillus thuringiensis var. israelensisLarval source managementMosquitoSublethal doseVector control

Identifiers

PMID32416733
PMCPMC7229702
OpenAlexW3027159972

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.