Evidence map›Paper›PMID 32416332›Full record

ArticleAmerican heart journal2020

Sarcopenia and health-related quality of life in older adults after transcatheter aortic valve replacement.

Abdulla A Damluji, Gregory Rodriguez, Thomas Noel, Lakerria Davis, Vishal Dahya, Behnam Tehrani, Kelly Epps, Matthew Sherwood, Eric Sarin, Jeremy Walston and 6 more

Open access · greenAbstract read
In one paragraph

Article in American heart journal, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed, 1 pooled it
3.0field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 1 synthesis or guideline pooled it, 32 citations in OpenAlex.

  1. Pooled it
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  17. Effect of sarcopenia on hospital stay from post cardiac surgery to discharge.International journal of cardiology. Heart & vasculature · 2022
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  20. The association between sarcopenia and quality of life in patients undergoing colorectal cancer surgery: an exploratory study.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 5 institutions in 1 country.

Abdulla A DamlujiInova Center of Outcomes Research, Inova Heart and Vascular Institute, Fairfax, VA; Division of Cardiology, Johns Hopkins University School of Medicine, Baltimore, MD.
Gregory RodriguezFlorida State University College of Medicine, Tallahassee, FL.
Thomas NoelSouthern Medical Group, P.A., Tallahassee, FL.
Lakerria DavisSouthern Medical Group, P.A., Tallahassee, FL.
Vishal DahyaSumma Health Medical Group, Akron, OH.
Behnam TehraniInova Center of Outcomes Research, Inova Heart and Vascular Institute, Fairfax, VA.
Kelly EppsInova Center of Outcomes Research, Inova Heart and Vascular Institute, Fairfax, VA.
Matthew SherwoodInova Center of Outcomes Research, Inova Heart and Vascular Institute, Fairfax, VA.
Eric SarinInova Center of Outcomes Research, Inova Heart and Vascular Institute, Fairfax, VA.
Jeremy WalstonDivision of Geriatric Medicine and Gerontology, Johns Hopkins University, Baltimore, MD.
Karen Bandeen-RocheDepartment of Biostatistics, Johns Hopkins School of Public Health, Baltimore, MD.
Jon R ResarDivision of Cardiology, Johns Hopkins University School of Medicine, Baltimore, MD.
Todd T BrownDivision of Endocrinology, Diabetes, and Metabolism, Johns Hopkins University, Baltimore, MD.
Gary GerstenblithDivision of Cardiology, Johns Hopkins University School of Medicine, Baltimore, MD.
Christopher M O'ConnorInova Center of Outcomes Research, Inova Heart and Vascular Institute, Fairfax, VA.
Wayne BatchelorInova Center of Outcomes Research, Inova Heart and Vascular Institute, Fairfax, VA. Electronic address: Wayne.Batchelor@inova.org.
Johns Hopkins Medicine · USJohns Hopkins University · USSouthern Medical Association · USFlorida State University · USSumma Health System · US

Funding

Technological Assessment and Solutions Core - RC4P30AG021334 · NIA · JOHNS HOPKINS UNIVERSITY · PI Jeremy D Walston · 2003 to 2026
$33.2M
Mentoring in Endocrine and Metabolic Abnormalities in HIV and AgingK24AI120834 · NIAID · JOHNS HOPKINS UNIVERSITY · PI BROWN, TODD T · 2015 to 2025
$1.8M
Frailty and Resiliency in Older Adults with Acute Myocardial InfarctionK23HL153771 · NHLBI · INOVA HEALTH CARE SERVICES · PI DAMLUJI, ABDULLA AL · 2020 to 2024
$916k
NHLBI NIH HHS K23 HL153771NIAID NIH HHS K24 AI120834NIA NIH HHS P30 AG021334
6 · The paper itself

Abstract

backgroundSkeletal muscle wasting, or sarcopenia, affects a significant proportion of patients undergoing transcatheter aortic valve replacement (TAVR). However, its influence on post-TAVR recovery and 1-year health-related quality of life (HR-QOL) remains unknown. We examined the relationship between skeletal muscle index (SMI), post-TAVR length of hospital stay (LOS), and 1-year QOL.

methodsThe study sample consisted of 300 consecutive patients undergoing TAVR from 2012 to 2018 who had pre-TAVR computed tomographic scans suitable for analysis of body composition. Skeletal muscle mass was quantified as cm

resultsSarcopenia was present in most (59%) patients and associated with older age (82 vs 76 years; P < .001) and lower body mass index (27 vs 33 kg/m

conclusionsSarcopenia is prevalent in TAVR patients. Higher SMI is associated with shorter LOS and better 1-year HR-QOL. To achieve optimal TAVR benefits, further study into how body composition influences post-TAVR recovery and durable improvement in QOL is warranted.

Indexed as

Health StatusQuality of LifeTranscatheter Aortic Valve ReplacementAgedAged, 80 and overAortic Valve StenosisCross-Sectional StudiesFemaleFloridaFollow-Up StudiesHumansMaleMuscle, SkeletalPostoperative PeriodPrevalenceRetrospective Studies

Identifiers

PMID32416332
PMCPMC8132132
OpenAlexW3014269316

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.