ArticleThe American journal of medicine2020
Changes in Care for Acute Pulmonary Embolism Through A Multidisciplinary Pulmonary Embolism Response Team.
Article in The American journal of medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers, 2 of them syntheses that pooled it.
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
28 citing papers in PubMed, 2 syntheses or guidelines pooled it, 63 citations in OpenAlex.
- Pulmonary embolism response team (PERT) implementation and its clinical value across countries: a scoping review and meta-analysis.Clinical research in cardiology : official journal of the German Cardiac Society · 2023Pooled it
- Impact of pulmonary embolism response teams on acute pulmonary embolism: a systematic review and meta-analysis.European respiratory review : an official journal of the European Respiratory Society · 2022Pooled it
- Outcomes of EKOS (Ultrasound-Assisted Thrombolysis) for Intermediate-High-Risk Pulmonary Embolism: A PERT-Guided Cohort Study.Interdisciplinary cardiovascular and thoracic surgery · 2026Article
- Process and outcome evaluation of a regional pulmonary embolism response team.Thrombosis journal · 2025Article
- Effects of Implementing a Standardized Risk Stratification and Triage Workflow for an Established Pulmonary Embolism Response Team.Annals of the American Thoracic Society · 2025Article
- Rethinking Pulmonary Embolism Management with an Interventional Perspective.Journal of clinical medicine · 2025Review
- Management of Hemodynamic and Respiratory Instability and Anesthetic Approaches in Patients Undergoing Pulmonary Thrombectomy for Pulmonary Embolism.Journal of clinical medicine · 2025Article
- A Practical Clinical Approach to Navigate Pulmonary Embolism Management: A Primer and Narrative Review of the Evolving Landscape.Journal of clinical medicine · 2024Review
- Pulmonary Embolism Response Teams-Evidence of Benefits? A Systematic Review and Meta-Analysis.Journal of clinical medicine · 2024Review
- Acute Pulmonary Embolism: Evidence, Innovation, and Horizons.Current cardiology reports · 2024Review
- Multidisciplinary Approach to Pulmonary Embolism and the Role of the Pulmonary Embolism Response Team.Current cardiology reports · 2024Review
- Evolution of Pulmonary Embolism Response Teams in the United States: A Review of the Literature.Journal of clinical medicine · 2024Review
- Reduced mortality associated with pulmonary embolism response team consultation for intermediate and high-risk pulmonary embolism: a retrospective cohort study.Thrombosis journal · 2024Article
- Risk Stratification and Management of Intermediate-Risk Acute Pulmonary Embolism.Journal of clinical medicine · 2024Review
- Treatment of high- and intermediate-high-risk pulmonary embolism by the Pulmonary Embolism Response Team: Focus on catheter-directed therapies.Cardiology journal · 2024Article
- The paradigm shift in treatment of severe venous thromboembolism.Jornal vascular brasileiro · 2024Review
- Clinical Significance of Right Heart Thrombus With and Without an Associated Pulmonary Embolism.The American journal of medicine · 2023Observational
- Interventional therapies for pulmonary embolism.Nature reviews. Cardiology · 2023Review
- Pulmonary embolism response team for hospitalized patients with submassive and massive pulmonary embolism: A single-center experience.Journal of vascular surgery. Venous and lymphatic disorders · 2023Article
- Percutaneous Management of High-Risk Pulmonary Embolism.Circulation. Cardiovascular interventions · 2023Review
Corrections and comments
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Authors and funding
20 authors at 2 institutions in 2 countries.
Funding
Abstract
backgroundOptimal management of acute pulmonary embolism requires expertise offered by multiple subspecialties. As such, pulmonary embolism response teams (PERTs) have increased in prevalence, but the institutional consequences of a PERT are unclear.
methodsWe compared all patients that presented to our institution with an acute pulmonary embolism in the 3 years prior to and 3 years after the formation of our PERT. The primary outcome was in-hospital pulmonary embolism-related mortality before and after the formation of the PERT. Sub-analyses were performed among patients with elevated-risk pulmonary embolism.
resultsBetween August 2012 and August 2018, 2042 patients were hospitalized at our institution with acute pulmonary embolism, 884 (41.3%) pre-PERT implementation and 1158 (56.7%) post-PERT implementation, of which 165 (14.2%) were evaluated by the PERT. There was no difference in pulmonary embolism-related mortality between the two time periods (2.6% pre-PERT implementation vs 2.9% post-PERT implementation, P = .89). There was increased risk stratification assessment by measurement of cardiac biomarkers and echocardiograms post-PERT implementation. Overall utilization of advanced therapy was similar between groups (5.4% pre-PERT implementation vs 5.4% post-PERT implementation, P = 1.0), with decreased use of systemic thrombolysis (3.8% pre-PERT implementation vs 2.1% post-PERT implementation, P = 0.02) and increased catheter-directed therapy (1.3% pre-PERT implementation vs 3.3% post-PERT implementation, P = 0.05) post-PERT implementation. Inferior vena cava filter use decreased after PERT implementation (10.7% pre-PERT implementation vs 6.9% post-PERT implementation, P = 0.002). Findings were similar when analyzing elevated-risk patients.
conclusionPulmonary embolism response teams may increase risk stratification assessment and alter application of advanced therapies, but a mortality benefit was not identified.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.