ReviewActa tropica2020
Beyond the barrier: Female Genital Schistosomiasis as a potential risk factor for HIV-1 acquisition.
Review in Acta tropica, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 51 papers, 6 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
51 citing papers in PubMed, 6 syntheses or guidelines pooled it, 64 citations in OpenAlex.
- Diagnostic accuracy of rapid and point-of-care tests forFrontiers in parasitology · 2026Pooled it
- The Global Prevalence of and Factors Associated with Parasitic Coinfection in People Living with Viruses: A Systematic Review and Meta-Analysis.Pathogens (Basel, Switzerland) · 2025Pooled it
- Association of female genital schistosomiasis and human papillomavirus and cervical pre-cancer: a systematic review.BMC women's health · 2025Pooled it
- Schistosomiasis-Microbiota Interactions: A Systematic Review and Meta-Analysis.Pathogens (Basel, Switzerland) · 2024Pooled it
- Behaviour change interventions for the control and elimination of schistosomiasis: A systematic review of evidence from low- and middle-income countries.PLoS neglected tropical diseases · 2023Pooled it
- Association of schistosomiasis and HIV infections: A systematic review and meta-analysis.International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases · 2021Pooled it
- Cervicovaginal Immune Activation in Zambian Women With Female Genital Schistosomiasis.Frontiers in immunology · 2021Trial
- Prevalence and associated risk factors of self-reported symptoms suggestive of female genital schistosomiasis (FGS) among women in KwaZulu-Natal, South Africa.PLoS neglected tropical diseases · 2026Article
- Acceptability and feasibility of one-stop home-based genital self-sampling for female genital schistosomiasis, human papilloma virus and self-testing for trichomonas and HIV: the Zipime Weka Schista study in Zambia.BMC women's health · 2026Article
- Female genital schistosomiasis-related infertility and gynecological manifestations among women living in countries endemic for urogenital schistosomiasis in Africa: systematic review and meta-analysis protocol.Systematic reviews · 2026Article
- Diagnostic competence and health worker knowledge of female genital schistosomiasis management in a rural Ghanaian district.PLoS neglected tropical diseases · 2026Article
- Diagnosis and treatment of female genital schistosomiasis.The Lancet. Microbe · 2026Review
- Imported female genital schistosomiasis: a neglected health issue across borders.Journal of global health · 2026Review
- Diagnosis of female genital schistosomiasis and pre-emptive treatment with praziquantel: a community-based pilot intervention study in Tiko, Cameroon.Reproductive health · 2026Article
- The burden and risk factors of female genital schistosomiasis in two schistosomiasis-endemic states of Nigeria.International health · 2025Article
- Review
- Scoping a social science agenda for male genital schistosomiasis in sub-Saharan Africa: posing key questions to frame appropriate research themes.Parasitology · 2025Article
- Using precision mapping of schistosomiasis to guide female genital schistosomiasis (FGS) screening in Cameroon, sub-Saharan Africa.Parasitology · 2025Article
- Article
- Now, more than ever, it's time to address the neglect of female genital schistosomiasis.Parasitology · 2025Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 1 institution in 1 country.
Funding
Abstract
Female genital schistosomiasis (FGS) results from egg-deposition in the female reproductive tract primarily by the waterborne parasite Schistosoma (S.) haematobium, and less commonly by Schistosoma (S.) mansoni. FGS affects an estimated 20-56 million women worldwide, mostly in sub-Saharan Africa. There is cross-sectional evidence of increased HIV-1 prevalence in schistosomiasis-infected women, but a causal relationship between FGS and either HIV-1 acquisition or transmission has not been fully established. Beyond the pathognomonic breach in the cervicovaginal barrier caused by FGS, this narrative review explores potential mechanisms for a synergistic relationship between S. haematobium infection, FGS, and HIV-1 acquisition through vaginal inflammation and target cell recruitment.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.