Evidence map›Paper›PMID 32415874›Full record

ArticleAngewandte Chemie (International ed. in English)2020

In Vivo Imaging of the Tumor-Associated Enzyme NCEH1 with a Covalent PET Probe.

Jae Won Chang, Mohammed Bhuiyan, Hsiu-Ming Tsai, Hannah J Zhang, Gang Li, Shaghayegh Fathi, David C McCutcheon, Lara Leoni, Richard Freifelder, Chin-Tu Chen and 1 more

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Angewandte Chemie (International ed. in English), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
0.9field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 21 citations in OpenAlex.

  1. Article
  2. Article
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  4. Article
  5. Review
  6. Chemical Probes and Activity-Based Protein Profiling for Cancer Research.International journal of molecular sciences · 2022
    Review
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  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 2 institutions in 1 country.

Jae Won ChangDepartment of Chemistry, The University of Chicago, 929 E. 57th St., Chicago, IL, 60637, USA.
Mohammed BhuiyanDepartment of Radiology, The University of Chicago, 5735 S. Ellis Ave, Chicago, IL, 60637, USA.
Hsiu-Ming TsaiIntegrated Small Animal Imaging Research Resource, The University of Chicago, 5735 S. Ellis Ave, Chicago, IL, 60637, USA.
Hannah J ZhangIntegrated Small Animal Imaging Research Resource, The University of Chicago, 5735 S. Ellis Ave, Chicago, IL, 60637, USA.
Gang LiDepartment of Chemistry, The University of Chicago, 929 E. 57th St., Chicago, IL, 60637, USA.
Shaghayegh FathiDepartment of Chemistry, The University of Chicago, 929 E. 57th St., Chicago, IL, 60637, USA.
David C McCutcheonDepartment of Chemistry, The University of Chicago, 929 E. 57th St., Chicago, IL, 60637, USA.
Lara LeoniIntegrated Small Animal Imaging Research Resource, The University of Chicago, 5735 S. Ellis Ave, Chicago, IL, 60637, USA.
Richard FreifelderDepartment of Radiology, The University of Chicago, 5735 S. Ellis Ave, Chicago, IL, 60637, USA.
Chin-Tu ChenIntegrated Small Animal Imaging Research Resource, The University of Chicago, 5735 S. Ellis Ave, Chicago, IL, 60637, USA.
Raymond E MoelleringDepartment of Chemistry, The University of Chicago, 929 E. 57th St., Chicago, IL, 60637, USA.ORCID 0000-0002-2043-7838
University of Chicago · USEmory University · US

Funding

VIRAL ONCOLOGY CORE FACILITYP30CA014599 · NCI · UNIVERSITY OF CHICAGO · PI CHIEN-MIN KAO · 1985 to 2026
$122.1M
Research Training in Digestive Health, Diseases, and NutritionT32DK007074 · NIDDK · UNIVERSITY OF CHICAGO · PI EUGENE B CHANG · 1986 to 2026
$11.3M
Integrating Preclinical and Translational Imaging Resources for Animal ResearchS10OD025265 · OD · UNIVERSITY OF CHICAGO · PI CHEN, CHIN-TU · 2018 to 2018
$319k
NCI NIH HHS P30 CA014599NIDDK NIH HHS T32 DK007074NIH HHS S10 OD025265
6 · The paper itself

Abstract

Herein, we report the development of an

Indexed as

AnimalsFemaleFluorine RadioisotopesHumansMicePositron-Emission TomographySterol EsteraseFluorine RadioisotopesNceh1 protein, mouseSterol Esteraseactivity-based probesimagingNCEH1positron emission tomographyradiotracers

Identifiers

PMID32415874
PMCPMC7748380
OpenAlexW3024943696

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.