Evidence map›Paper›PMID 32415833›Full record

ArticleAmerican journal of epidemiology2020

Invited Commentary: Frontiers of Power Assessment in Mediation Analysis.

Tyler J VanderWeele

Abstract readComment
In one paragraph

Article in American journal of epidemiology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Intersections Among Attachment, Empathy and Emotion Regulation in Middle Childhood.International journal of psychology : Journal international de psychologie · 2026
    Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Review
  7. Rudolph et al. Respond to "Power in Mediation Analysis".American journal of epidemiology · 2020
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

1 author.

Tyler J VanderWeele

Funding

Theory and methods for mediation and interactionR01CA222147 · NCI · HARVARD SCHOOL OF PUBLIC HEALTH · PI TCHETGEN TCHETGEN, ERIC JOEL, VANDERWEELE, TYLER · 2018 to 2022
$2.1M
NCI NIH HHS R01 CA222147
6 · The paper itself

Abstract

The development of tools for power and sample-size calculations for mediation analysis has lagged far behind the development of methods. The accompanying paper by Rudolph et al. (Am J Epidemiol. 2020;189(12):1559-1567) is a helpful contribution in using simulations as a tool for power calculations for more complex methods and settings. Much work remains to be done in the development of easy-to-use packages and simple online websites for carrying out power and sample-size calculations for mediation analysis. Much remains to be learned with respect to the relative power of different methods in different settings. There will likely be feedback between these 2 important frontiers of the tools we have available and of our understanding of power when conducting mediation analysis.

Indexed as

Mediation AnalysisComputer SimulationHumansdirect and indirect effectsmediationpowersample sizesoftwarestatistics

Identifiers

PMID32415833
PMCPMC8453227

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.