SynthesisEuropean radiology2020
Diagnostic performance of conventional and advanced imaging modalities for assessing newly diagnosed cervical cancer: systematic review and meta-analysis.
Synthesis in European radiology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 40 papers, 1 of them a synthesis that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
40 citing papers in PubMed, 1 synthesis or guideline pooled it, 79 citations in OpenAlex.
- EANM/SNMMI practice guideline for [European journal of nuclear medicine and molecular imaging · 2021Guideline
- MRI-defined parametrial venous invasion in locally advanced cervical cancer: association with pathological venous invasion, pretreatment lymph node metastasis, and survival outcomes.Japanese journal of radiology · 2026Article
- Node-RADS in cervical cancer: a multi-reader agreement and diagnostic performance study.Cancer imaging : the official publication of the International Cancer Imaging Society · 2026Article
- Diagnostic utility of apparent diffusion coefficient values in cervical cancer staging: A retrospective study.European journal of radiology open · 2026Article
- The challenges of implementing less invasive surgical management for cervical cancer in a limited-resource setting in Botswana: A case series.Gynecologic oncology reports · 2026Article
- Multiparametric MRI-based Deep Learning and Radiomics for Evaluating Lymph Node Metastasis in Early-Stage Cervical Cancer.Radiology. Imaging cancer · 2026Article
- Primary tumor-derived, multiparametric MRI-based deep learning-radiomics-clinical model for predicting lymph node metastasis in early-stage cervical cancer.Insights into imaging · 2026Article
- Integrating domain-specific convolutional features with Swin Transformers for transparent cervical cancer diagnostics.Frontiers in oncology · 2026Article
- Examined lymph node counts affected the staging and survival in cervical cancer: a retrospective study using the SEER and Chinese cohort.Annals of medicine · 2025Article
- Assessing the Clinical Utility of MRI for Preoperative Staging of Early-Stage Cervical Cancer in a Limited-Resource Setting: A Retrospective Cohort Study from Botswana.Research square · 2025Article
- Added value of radiological staging to clinical examination in different histopathological subtypes of uterine cervical cancer: A retrospective study.European journal of obstetrics & gynecology and reproductive biology: X · 2025Article
- Limited diagnostic performance of imaging evaluation for staging in gastric-type endocervical adenocarcinoma: a multi-center study.Japanese journal of radiology · 2025Article
- Magnetic resonance imaging and ultrasound examination in preoperative pelvic staging of early-stage cervical cancer: post-hoc analysis of SENTIX study.Ultrasound in obstetrics & gynecology : the official journal of the International Society of Ultrasound in Obstetrics and Gynecology · 2025Article
- Assessing the Efficacy of 18F FDG PET-CT in Preoperative Staging of Early-Stage Cervical Cancer in Novi Sad, Serbia-A Pilot Study.Journal of clinical medicine · 2024Article
- Comparative Diagnostic Value of 18F-FDG-PET-CT and Intraoperative Examination in Cervical Cancer Staging.Medicina (Kaunas, Lithuania) · 2024Article
- The Polish Society of Gynecological Oncology Guidelines for the Diagnosis and Treatment of Cervical Cancer (v2024.0).Journal of clinical medicine · 2024Article
- Autocrine and paracrine effects of MDK promote lymph node metastasis of cervical squamous cell carcinoma.iScience · 2024Article
- The value of contrast-enhanced ultrasound in cervical cancer assessed in comparison with magnetic resonance imaging.Medicine and pharmacy reports · 2024Article
- The value of MRI in quantification of parametrial invasion and association with prognosis in locally advanced cervical cancer: the "PLACE" study.European radiology · 2024Observational
- The Role of Imaging in Cervical Cancer Staging: ESGO/ESTRO/ESP Guidelines (Update 2023).Cancers · 2024Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 3 institutions in 2 countries.
Funding
Abstract
objectivesTo review the diagnostic performance of contemporary imaging modalities for determining local disease extent and nodal metastasis in patients with newly diagnosed cervical cancer.
methodsPubmed and Embase databases were searched for studies published from 2000 to 2019 that used ultrasound (US), CT, MRI, and/or PET for evaluating various aspects of local extent and nodal metastasis in patients with newly diagnosed cervical cancer. Sensitivities and specificities from the studies were meta-analytically pooled using bivariate and hierarchical modeling.
resultsOf 1311 studies identified in the search, 115 studies with 13,999 patients were included. MRI was the most extensively studied modality (MRI, CT, US, and PET were evaluated in 78, 12, 9, and 43 studies, respectively). Pooled sensitivities and specificities of MRI for assessing all aspects of local extent ranged between 0.71-0.88 and 0.86-0.95, respectively. In assessing parametrial invasion (PMI), US demonstrated pooled sensitivity and specificity of 0.67 and 0.94, respectively-performance levels comparable with those found for MRI. MRI, CT, and PET performed comparably for assessing nodal metastasis, with low sensitivity (0.29-0.69) but high specificity (0.88-0.98), even when stratified to anatomical location (pelvic or paraaortic) and level of analysis (per patient vs. per site).
conclusionsMRI is the method of choice for assessing any aspect of local extent, but where not available, US could be of value, particularly for assessing PMI. CT, MRI, and PET all have high specificity but poor sensitivity for the detection of lymph node metastases. KEY POINTS: • Magnetic resonance imaging is the method of choice for assessing local extent. • Ultrasound may be helpful in determining parametrial invasion, especially in lower-resourced countries. • Computed tomography, magnetic resonance imaging, and positron emission tomography perform similarly for assessing lymph node metastasis, with high specificity but low sensitivity.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.