Evidence map›Paper›PMID 32415580›Full record

ArticleJournal of biomolecular NMR2020

Backbone assignments and conformational dynamics in the S. typhimurium tryptophan synthase α-subunit from solution-state NMR.

Varun V Sakhrani, Eduardo Hilario, Bethany G Caulkins, Mary E Hatcher-Skeers, Li Fan, Michael F Dunn, Leonard J Mueller

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of biomolecular NMR, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.4field-weighted citation impact, top 40% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. Article
  3. Solution-state nuclear magnetic resonance studies of theBiochemistry and biophysics reports · 2026
    Article
  4. Article
  5. Allosteric regulation of substrate channeling:Frontiers in molecular biosciences · 2022
    Review
  6. Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Varun V SakhraniDepartment of Chemistry, University of California Riverside, Riverside, CA, 92521, USA.
Eduardo HilarioDepartment of Chemistry, University of California Riverside, Riverside, CA, 92521, USA.
Bethany G CaulkinsKeck Science Department, Claremont McKenna, Pitzer, and Scripps Colleges, Claremont, CA, 91711, USA.
Mary E Hatcher-SkeersKeck Science Department, Claremont McKenna, Pitzer, and Scripps Colleges, Claremont, CA, 91711, USA.
Li FanDepartment of Biochemistry, University of California Riverside, Riverside, CA, 92521, USA.
Michael F DunnDepartment of Biochemistry, University of California Riverside, Riverside, CA, 92521, USA.
Leonard J MuellerDepartment of Chemistry, University of California Riverside, Riverside, CA, 92521, USA. leonard.mueller@ucr.edu.ORCID http://orcid.org/0000-0002-2607-9875
University of California, Riverside · USScripps College · US

Funding

Chemically-Rich Structure and Dynamics in the Active Site of Tryptophan SynthaseR01GM097569 · NIGMS · UNIVERSITY OF CALIFORNIA RIVERSIDE · PI MUELLER, LEONARD J · 2011 to 2020
$2.9M
National Science Foundation CHE1710671NIGMS NIH HHS R01 GM097569NIH HHS GM097569
6 · The paper itself

Abstract

Backbone assignments for the isolated α-subunit of Salmonella typhimurium tryptophan synthase (TS) are reported based on triple resonance solution-state NMR experiments on a uniformly

Indexed as

Bacterial ProteinsBinding SitesCatalysisCrystallography, X-RayModels, MolecularMolecular Dynamics SimulationNitrogen IsotopesNuclear Magnetic Resonance, BiomolecularProtein ConformationProtein Structure, SecondaryProtein SubunitsSalmonella typhimuriumSolutionsTryptophan SynthaseBacterial ProteinsNitrogen-15Nitrogen IsotopesProtein SubunitsSolutionsTryptophan SynthaseChemical shift assignmentsLigand titrationProtein dynamicsProtein NMRRelaxationTryptophan synthase

Identifiers

PMID32415580
PMCPMC7451264
OpenAlexW3024848913

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.