ArticleLa Radiologia medica2020
Current role of computed tomography imaging in the evaluation of cartilage invasion by laryngeal carcinoma.
Article in La Radiologia medica, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
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13 citing papers in PubMed, 18 citations in OpenAlex.
- Practical applications of photon-counting CT in oncology: an organ-based pictorial review.Insights into imaging · 2026Article
- CT imaging of thyroid cartilage invasion in glottic laryngeal cancer: correlation of traditional semiotics and texture analysis with histopathology.La Radiologia medica · 2026Article
- Clinical-pathological T-stage discrepancy in OPHL: impact on oncologic outcomes.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2026Article
- Predicting Local Recurrence in T3 Laryngeal Squamous Cell Carcinoma: An Analysis of Tumor Volume and Cartilage Invasion Prior to Radiotherapy.Cancer medicine · 2026Article
- CT-based radiomics and deep learning models for predicting thyroid cartilage invasion and patient prognosis in laryngeal carcinoma.Scientific reports · 2025Article
- Is the Ensemble Machine Learning Model a Reliable Method for Detecting Neoplastic Infiltration of Thyroid Cartilage in Laryngeal Cancers?Medicina (Kaunas, Lithuania) · 2025Article
- CT acquisition protocols by pathology, SIRM position paper part 1: head and neck, brain and spine, chest, cardiovascular.La Radiologia medica · 2025Article
- Clinical and Pathological Staging Discrepancies in Laryngeal Cancer: A Systematic Review.Cancers · 2025Review
- Discrepancy between clinical and pathological staging of laryngeal carcinoma: a dilemma to be solved.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2024Article
- Integration between Novel Imaging Technologies and Modern Radiotherapy Techniques: How the Eye Drove the Chisel.Cancers · 2022Review
- Reliability of a Multidisciplinary Multiparametric Approach in the Surgical Planning of Laryngeal Squamous Cell Carcinomas: A Retrospective Observational Study.Journal of personalized medicine · 2022Article
- The impact of patient preference in the treatment algorithm for recurrent/metastatic head and neck squamous cell carcinoma.La Radiologia medica · 2022Article
- Diffusion weighted imaging and diffusion kurtosis imaging in abdominal oncological setting: why and when.Infectious agents and cancer · 2022Review
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Authors and funding
12 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectivesTo evaluate thyroid, arytenoid, and cricoid cartilage invasion on computed tomography (CT) imaging in patients undergoing total laryngectomy for both primary and recurrent laryngeal carcinoma. Secondary endpoint was to compare laryngeal cartilage invasion between primary and recurrent tumours.
methodsPre-treatment CT of 40 patients who had undergone total laryngectomy was retrospectively evaluated and compared with histology. Focal erosions of thyroid cartilage were accounted for neoplastic invasion of the inner cortex. Full-thickness thyroid cartilage invasion was defined as a tumour-like tissue replacing thyroid cartilage or extended in extra-laryngeal soft tissues. Sclerosis and erosion of arytenoid and cricoid cartilages were assessed as signs of neoplastic invasion.
resultsCT erosion showed perfect agreement for thyroid inner cortex and cricoid cartilage invasion and almost perfect agreement (87%) for arytenoid cartilage invasion. For tumours in contact with thyroid cartilages, the absence of CT erosion underestimated inner cortex infiltration. CT showed perfect agreement in predicting full-thickness thyroid cartilage invasion only in the case of extra-laryngeal neoplastic extension. Arytenoid sclerosis showed poor correlation with neoplastic invasion. For primary tumours, CT demonstrated good (inner cortex 75%; full-thickness 85%), substantial (67.5%), and perfect (100%) accuracy in thyroid, arytenoid, and cricoid cartilage invasion, respectively. No CT differences were observed between primary and recurrent laryngeal tumours.
conclusionTumour-like tissue extension in the extra-laryngeal soft tissues was accurate in predicting thyroid cartilage full-thickness invasion. Erosions of arytenoid, cricoid, and thyroid cartilages' inner cortex on CT were highly indicative of neoplastic infiltration. No CT difference in cartilage infiltration between primary and recurrent tumours was observed.
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