ArticleClinical oral investigations2020
Peri-implant disease affects systemic complete blood count values-an experimental in vivo study.
Article in Clinical oral investigations, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.
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Who cites it
13 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Association between peri-implantitis and systemic inflammation: a systematic review.Frontiers in immunology · 2023Pooled it
- Biomarker-Guided Implant Maintenance (BGIM): A Narrative Review and Protocol Proposal.Journal of clinical medicine · 2026Review
- Peri-implantitis: a systemic burden for our patients.Frontiers in dental medicine · 2026Review
- Dysregulation of the Immune System in Advanced Periimplantitis: Systemic Implications and Inflammatory Mechanisms-A Hematological and Immunological Study.Journal of clinical medicine · 2025Article
- The systemic impact of non-surgical treatment of peri-implantitis with or without adjunctive systemic metronidazole: Secondary analysis of a randomized clinical trial.Clinical oral implants research · 2024Article
- Induction of Experimental Peri-Implantitis with Strains Selected from the Human Oral Microbiome.Biomedicines · 2024Article
- Evaluation of clinical and serological responses after full-mouth implantation in single-visit versus multiple-session surgery.Journal of advanced periodontology & implant dentistry · 2024Article
- Referral Patterns of General Dental Practitioners for Implant Surgery Procedures.Oral health & preventive dentistry · 2023Article
- Anti-Peri-implantitis Bacteria's Ability of Robusta Green Coffee Bean (Coffea Canephora) Ethanol Extract: An In Silico and In Vitro Study.European journal of dentistry · 2023Article
- Reversal of Osseointegration as a Novel Perspective for the Removal of Failed Dental Implants: A Review of Five Patented Methods.Materials (Basel, Switzerland) · 2021Review
- Peri-implantitis, systemic inflammation, and dyslipidemia: a cross-sectional biochemical study.Journal of periodontal & implant science · 2021Article
- Surgical Treatment of Sialolithiasis Leads to Improvement in the Complete Blood Count.Biology · 2021Article
- The Impact of Peri-Implantitis on Systemic Diseases and Conditions: A Review of the Literature.International journal of dentistry · 2021Review
Corrections and comments
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Authors and funding
5 authors.
Funding
Abstract
objectivesTo assess complete blood count (CBC) dynamics following ligature removal and open flap debridement in experimental peri-implantitis in dogs. MATERIALS AND
methodsSeven male beagle dogs were included in the study. Four rough-surface implants were placed pair-wise in both sides of the mandible 14 weeks after tooth extraction. Second stage surgery was performed after 14 weeks. Experimental peri-implantitis was initiated 3 weeks later by ligature placement around the healing caps thus facilitating plaque accumulation and inducing inflammation and destruction of peri-implant tissues. Ligature removal and open flap debridement were performed 11 weeks later. The CBC values were compared with baseline after each procedure. Wilcoxon paired tests were conducted in order to identify statistically significant differences between baseline data and values obtained after each procedure.
resultsFollowing experimental peri-implantitis, statistically significant (p < 0.05) increases were noted for white blood cells-WBC (9.62 ± 4.34 vs. 6.48 ± 1.34 cells per microliter of blood × 1000), hemoglobin-Hb (15.25 ± 0.94 vs. 13.52 ± 1.46, grams per deciliter), red blood cells-RBC (7.26 ± 0.79 vs. 5.9 ± 0.61 cells per microliter of blood × 1000), mean corpuscular hemoglobin-MCH (23.64 ± 0.96 vs. 23.16 ± 0.83 picograms/cell), platelets-PLT (349.86 ± 51.05 vs. 277.57 ± 66 cells per microliter of blood × 1000), and mean corpuscular hemoglobin concentration-MCHC (35.83 ± 0.27 vs. 31.04 ± 0.48 grams per deciliter). A statistically significant (p < 0.05) decrease in values was noted only for after ligature removal and open flap debridement. Mean corpuscular volume-MCV values were significantly lower (65.99 ± 2.31 vs. 74.65 ± 2.85 femtoliter) following 1
conclusionsWithin its limits, the present data suggest that experimentally induced peri-implantitis affects CBC values. Following surgical treatment, CBC values returned to normal. Clinical relevance This is the first study suggesting possible relationships between peri-implantitis and CBC values. Future studies, confirming such correlation, may provide an insight into the importance of peri-implant maintenance and treatment to minimize supporting tissues disease and reduce systemic effects.
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