Evidence map›Paper›PMID 32415386›Full record

SynthesisSupportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer2020

Resistance exercise and breast cancer-related lymphedema-a systematic review update and meta-analysis.

Timothy Hasenoehrl, Stefano Palma, Dariga Ramazanova, Heinz Kölbl, Thomas E Dorner, Mohammad Keilani, Richard Crevenna

2 registry-linked trialsOpen access · hybridAbstract readMeta-AnalysisSystematic Review
PubMed Full text at PMC Publisher
In one paragraph

Synthesis in Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 80 papers, 7 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
80citing papers in PubMed, 7 pooled it
4.7field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06952270 nanot yet recruitingnot on this mapstarted 2025, after this paper: background citation

Effects of Two Strength Exercise Programs on Upper Limb Functionality in Breast Cancer

TypeinterventionalSponsorUniversity of VigoRan2025 to 2025Enrolled24ConditionsBreast Cancer Survivor, Breast Cancer, Breast Cancer Patients, Breast Cancer - FemaleArmsplyometric exercise, Strength training exercise
NCT07460492 nanot yet recruitingnot on this mapstarted 2026, after this paper: background citation

Therapeutic Plyometric-Based Strength-Endurance Exercise Program for Breast Cancer Patients and Survivors to Improve Quality of Life and Physical and Mental Function

TypeinterventionalSponsorUniversity of VigoRan2026 to 2027Enrolled51ConditionsNeoplams, Patients, Cancer SurvivorsArmsPlyometric Strength-Endurance Training, Conventional Strength Training
3 · Its place in the literature

Who cites it

80 citing papers in PubMed, 7 syntheses or guidelines pooled it, 125 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Pooled it
  5. Effects of resistance training on breast cancer-related arm lymphedema: a systematic review and dose-response meta-analysis.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2025
    Pooled it
  6. Pooled it
  7. Pooled it
  8. Trial
  9. Trial
  10. Trial
  11. The effect of muscles in the treatment of lower limb lymphedema: respiratory muscles or leg muscles?Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2025
    Trial
  12. Preventive effects of progressive resistance training of different intensities on breast cancer-related lymphedema.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2025
    Trial
  13. Trial
  14. Trial
  15. Impact of Inertial Training on Muscle Strength and Quality of Life in Breast Cancer Survivors.International journal of environmental research and public health · 2022
    Trial
  16. Current status of lymphedema-related health information-seeking behavior and its associated factors among postoperative breast cancer patients: a cross-sectional study.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2026
    Article
  17. Article
  18. Observational
  19. Article
  20. The impact of age factors on postoperative limb function recovery in breast cancer.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2026
    Article

20 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Timothy HasenoehrlDepartment of Physical Medicine, Rehabilitation and Occupational Medicine, Medical University of Vienna, Waehringer Guertel 18-20, 1090, Vienna, Austria.ORCID https://orcid.org/0000-0001-8263-6720
Stefano PalmaDepartment of Physical Medicine, Rehabilitation and Occupational Medicine, Medical University of Vienna, Waehringer Guertel 18-20, 1090, Vienna, Austria.
Dariga RamazanovaSection of Medical Statistics, CeMSIIS, Medical University of Vienna, Vienna, Austria.
Heinz KölblDivision for General Gynaecology and Gynaecological Oncology, Department of Gynaecology and Obstetrics, Medical University of Vienna, Vienna, Austria.
Thomas E DornerDepartment of Social and Preventive Medicine, Centre for Public Health, Medical University of Vienna, Vienna, Austria.
Mohammad KeilaniDepartment of Physical Medicine, Rehabilitation and Occupational Medicine, Medical University of Vienna, Waehringer Guertel 18-20, 1090, Vienna, Austria.
Richard CrevennaDepartment of Physical Medicine, Rehabilitation and Occupational Medicine, Medical University of Vienna, Waehringer Guertel 18-20, 1090, Vienna, Austria. richard.crevenna@meduniwien.ac.at.ORCID https://orcid.org/0000-0002-9177-0101
Medical University of Vienna · ATAustrian Federal Railways · AT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe purpose of this systematic review update and meta-analysis was to analyze resistance exercise (RE) intervention trials in breast cancer survivors (BCS) regarding their effect on breast cancer-related lymphedema (BCRL) status and upper and lower extremity strength.

methodsSystematic literature search was conducted utilizing PubMed, MEDLINE, and Embase databases. Any exercise intervention studies-both randomized controlled and uncontrolled-which assessed the effects of RE on BCRL in BCS in at least one intervention group published between 1966 and 31st January 2020 were included. Included articles were analyzed regarding their level of evidence and their methodological quality using respective tools for randomized and nonrandomized trials of the Cochrane collaboration. Meta-analysis for bioimpedance spectroscopy (BIS) values as well as upper and lower extremity strength was conducted.

resultsAltogether, 29 studies were included in the systematic review. Results of six studies with altogether twelve RE intervention groups could be pooled for meta-analysis of the BCRL. A significant reduction of BCRL after RE was seen in BIS values (95% CI - 1.10 [- 2.19, - 0.01] L-Dex score). Furthermore, strength results of six studies could be pooled and meta-analysis showed significant improvements of muscular strength in the upper and lower extremities (95% CI 8.96 [3.42, 14.51] kg and 95% CI 23.42 [11.95, 34.88] kg, respectively).

conclusionRE does not have a systematic negative effect on BCRL and, on the contrary, potentially decreases it.

Indexed as

Breast Cancer LymphedemaCancer SurvivorsElectric ImpedanceFemaleHumansRandomized Controlled Trials as TopicResistance TrainingBreast cancer survivorsBreast neoplasmLymphedema assessmentMedical training therapyResistance trainingSecondary lymphedemaStrength

Identifiers

PMID32415386
PMCPMC7316683
OpenAlexW3024577395

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.