ArticleThe Egyptian heart journal : (EHJ) : official bulletin of the Egyptian Society of Cardiology2020
Correlation between global longitudinal strain and SYNTAX score in coronary artery disease evaluation.
Article in The Egyptian heart journal : (EHJ) : official bulletin of the Egyptian Society of Cardiology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
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11 citing papers in PubMed.
- Time-aligned segmental strain as a diagnostic marker for obstructive coronary artery disease in patients with chronic chest pain.Cardiovascular ultrasound · 2026Review
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- Improving Stress Echocardiography for Enhanced Detection of Left Main and Multivessel Coronary Artery Disease.CJC open · 2026Article
- Pressure-strain loop evaluation of myocardial work in patients with coronary artery disease and preserved left ventricular ejection fraction: a retrospective study based on propensity score matching.European journal of medical research · 2025Article
- Global longitudinal strain in the prediction of significant coronary artery disease: how accurate is it for patients with a high clinical probability of chronic coronary syndrome and preserved left ventricular ejection fraction?Echo research and practice · 2025Article
- Evaluation of changes in the global longitudinal strain for left ventricular function before and after eight weeks of taking high dose of atorvastatin in patients with coronary slow flow phenomenon.BMC cardiovascular disorders · 2024Article
- Early Systolic Lengthening Is Associated with SYNTAX Score in Patients with Non-ST-Elevation Acute Coronary Syndrome.Anatolian journal of cardiology · 2023Article
- Article
- The correlation between speckle-tracking echocardiography and coronary angiography in suspected coronary artery disease with normal left ventricular function.Journal of cardiovascular and thoracic research · 2022Article
- Clinical Relevance of Right Atrial Strain Using Speckle-tracking Echocardiography: Emerging Insights and Future Prospective.Journal of cardiovascular echographyReview
- The diagnostic accuracy of two-dimensional strain imaging echocardiography to detect the severity of coronary artery disease in non-ST segment elevation acute coronary syndrome.Indian heart journalObservational
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Abstract
backgroundSpeckle tracking echocardiography may allow the evaluation of myocardial systolic and diastolic dynamics across different physiologic and pathologic conditions beyond traditional echocardiographic techniques. The use of STE longitudinal strain in identification and risk stratification of CAD has good reproducibility and accuracy. The study aims to detect the relationship between SYNTAX score and global longitudinal peak systolic strain (GLPSS) in patients undergoing coronary angiography, with no history of myocardial infarction.
resultsThe study included 70 symptomatic patients suspected to have chronic coronary syndrome aging 20-80 years (excluding those with significant structural heart disease). All patients underwent clinical evaluation, surface ECG, laboratory assessment, transthoracic echocardiographic (TTE), color TDI tracings, two-dimensional speckle tracking, and conventional coronary angiography with SYNTAX score calculation. Patients were divided into 3 groups based on the results of the coronary angiogram: normal CAD on angiogram (n = 10, control group), low SS (n = 25, SS < 22), and high SS (n = 35, SS ≥ 22). The mean age was 55 ± 9.6 years; 54% were males; two third of patients were hypertensive; 52% were diabetic; high percentage of high syntax score were noticed among males, diabetic patients, and smokers; and also low mean of GLS was noticed among diabetic patients and smokers. There was a statistically significant positive correlation between syntax score and each of LVEDD and LVESD and, on the other hand, statistically significant negative correlation between syntax score and each of E/A, GLS, AP2LS, AP3LS, and AP4LS was noticed. Peak GLS cutoff value of 17.8 and 16.5 showed 84% and 93% sensitivity and 70% and 91% specificity to detect high and low syntax score, respectively.
conclusion2D longitudinal strain analysis has incremental diagnostic value over visual assessment during echocardiography in predicting significant coronary artery disease; GLS may offer a potential sensitive tool to detect significant CAD.
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