Evidence map›Paper›PMID 32415247›Full record

ArticleScientific reports2020

Obesity and Diabetes in an Arab population: Role of Adenovirus 36 Infection.

Nader Lessan, Koramannil R Saradalekshmi, Budour Alkaf, Maria Majeed, Maha T Barakat, Zendra P L Lee, Richard L Atkinson

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 1 pooled it
2.5field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 1 synthesis or guideline pooled it, 21 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Observational
  4. Review
  5. Article
  6. Article
  7. Article
  8. Article
  9. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 2 countries.

Nader LessanImperial College London Diabetes Centre, Abu Dhabi, UAE. nlessan@icldc.ae.
Koramannil R SaradalekshmiImperial College London Diabetes Centre, Abu Dhabi, UAE.
Budour AlkafImperial College London Diabetes Centre, Abu Dhabi, UAE.
Maria MajeedImperial College London Diabetes Centre, Abu Dhabi, UAE.
Maha T BarakatImperial College London Diabetes Centre, Abu Dhabi, UAE.
Zendra P L LeeObetech Obesity Research Center, Richmond, VA, USA.
Richard L AtkinsonVirginia Commonwealth University, Richmond, VA, USA.
Imperial College London Diabetes Centre · AEVirginia BioTechnology Research Park · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Prior infection with adenovirus 36 (Adv36) has been associated with increased adiposity, improved insulin sensitivity, and a lower prevalence of diabetes. This study investigated the prevalence of Adv36 seropositivity and its association with obesity and diabetes among adults attending a diabetes centre in the UAE.Participants (N = 973) with different weight and glucose tolerance categories were recruited. Adv36 seropositivity (Adv36 + ) was assessed using ELISA. Differences among groups were analyzed using statistical tests as appropriate to the data. Prevalence of Adv36+ in the study population was 47%, with no significant difference in obese and non-obese subgroups (42.5% vs 49.6% respectively; p=non-significant). Females were more likely to be Adv36+ compared to males (odds ratio 1.78; 95% CI 1.36-2.32, p < 0.001). We found no significant association between Adv36 seropositivity and different BMI categories, or glucose tolerance status. In our population, the effect of Adv36 infection on lipid profile varied between healthy individuals and individuals with obesity. Adv36 infection is more prevalent in the UAE than in other countries but has no association with obesity. Our study found that females were more likely to be Adv36 positive regardless of weight or diabetes status.

Indexed as

AdiposityInsulin ResistanceAdenoviruses, HumanAdenovirus Infections, HumanAdultArabsBiomarkersBlood GlucoseBody WeightCase-Control StudiesDiabetes MellitusFemaleFollow-Up StudiesGlycated HemoglobinHumansMaleBiomarkersBlood GlucoseGlycated Hemoglobinhemoglobin A1c protein, human

Identifiers

PMID32415247
PMCPMC7229214
OpenAlexW3025425281

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.