ArticleNature communications2020
Large-scale network analysis captures biological features of bacterial plasmids.
Article in Nature communications, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 72 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
72 citing papers in PubMed, 133 citations in OpenAlex.
- Plasmidomics: studying plasmids as ecological entities beyond their hosts.Microbial genomics · 2026Review
- The shared evolutionary capacities of plasmids and extrachromosomal DNA.Nature reviews. Genetics · 2026Review
- Ecological theory sheds light on plasmid diversity and dynamics.PLoS biology · 2026Article
- A family of endonucleases blocks nanotube-mediated plasmid exchange.Nature microbiology · 2026Article
- Origin of replication discovery for environmentally isolatediScience · 2026Article
- Comparative Analysis of Lineage Structure, Cellulose Locus Context, and Mobilome Diversity Across CompleteMicroorganisms · 2026Article
- Plasmid-Driven Resistome Diversity in 9700Antibiotics (Basel, Switzerland) · 2026Article
- Plasmidomic landscape of Staphylococcus aureus and the emergence of a CC5 subclade harboring the conjugative plasmid pSK41: implications for food safety and antimicrobial resistance.NPJ science of food · 2026Article
- Plasmids as persistent genetic reservoirs of bacterial defense systems in wastewater treatment.Microbiome · 2026Article
- Beyond borders: plasmids drive a shared antibiotic resistome in European urban water systems.Microbiome · 2026Article
- Benchmarking overlapping community detection methods for applications in human connectomics.Network neuroscience (Cambridge, Mass.) · 2026Article
- Challenges and considerations for whole-genome-based antimicrobial resistance plasmid investigations.Antimicrobial agents and chemotherapy · 2025Review
- Plasmid transmission dynamics and evolution of partner quality in a natural population ofmBio · 2025Article
- ProFiT-SPEci-FISH: a novel approach for linking plasmids to hosts in complex microbial communities at the single-cell level.Microbiome · 2025Article
- A global soil plasmidome resource unveils functional and ecological roles of plasmids in soil microbiomes.Nature communications · 2025Article
- Horizontal gene transfer, segregation loss, and the speed of microbial adaptation.Evolution letters · 2025Article
- Scaling laws of bacterial and archaeal plasmids.Nature communications · 2025Article
- A phylogenetic approach to comparative genomics.Nature reviews. Genetics · 2025Review
- Unveiling plasmid diversity and functionality in pristine groundwater.Environmental microbiome · 2025Article
- Piggybacking on nature: exploring the multifaceted world of porcine β-defensins.Veterinary research · 2025Review
12 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 2 institutions in 1 country.
Funding
Abstract
Many bacteria can exchange genetic material through horizontal gene transfer (HGT) mediated by plasmids and plasmid-borne transposable elements. Here, we study the population structure and dynamics of over 10,000 bacterial plasmids, by quantifying their genetic similarities and reconstructing a network based on their shared k-mer content. We use a community detection algorithm to assign plasmids into cliques, which correlate with plasmid gene content, bacterial host range, GC content, and existing classifications based on replicon and mobility (MOB) types. Further analysis of plasmid population structure allows us to uncover candidates for yet undescribed replicon genes, and to identify transposable elements as the main drivers of HGT at broad phylogenetic scales. Our work illustrates the potential of network-based analyses of the bacterial 'mobilome' and opens up the prospect of a natural, exhaustive classification framework for bacterial plasmids.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.