Evidence map›Paper›PMID 32415137›Full record

ArticleScientific reports2020

An Automated Segmentation Pipeline for Intratumoural Regions in Animal Xenografts Using Machine Learning and Saturation Transfer MRI.

Wilfred W Lam, Wendy Oakden, Elham Karami, Margaret M Koletar, Leedan Murray, Stanley K Liu, Ali Sadeghi-Naini, Greg J Stanisz

Abstract read
In one paragraph

Article in Scientific reports, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Wilfred W LamPhysical Sciences, Sunnybrook Research Institute, Toronto, ON, Canada. lamw@sri.utoronto.ca.
Wendy OakdenPhysical Sciences, Sunnybrook Research Institute, Toronto, ON, Canada.
Elham KaramiPhysical Sciences, Sunnybrook Research Institute, Toronto, ON, Canada.
Margaret M KoletarPhysical Sciences, Sunnybrook Research Institute, Toronto, ON, Canada.
Leedan MurrayPhysical Sciences, Sunnybrook Research Institute, Toronto, ON, Canada.
Stanley K LiuMedical Biophysics, University of Toronto, Toronto, ON, Canada.
Ali Sadeghi-NainiPhysical Sciences, Sunnybrook Research Institute, Toronto, ON, Canada.
Greg J StaniszPhysical Sciences, Sunnybrook Research Institute, Toronto, ON, Canada.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Saturation transfer MRI can be useful in the characterization of different tumour types. It is sensitive to tumour metabolism, microstructure, and microenvironment. This study aimed to use saturation transfer to differentiate between intratumoural regions, demarcate tumour boundaries, and reduce data acquisition times by identifying the imaging scheme with the most impact on segmentation accuracy. Saturation transfer-weighted images were acquired over a wide range of saturation amplitudes and frequency offsets along with T

Indexed as

AlgorithmsMachine LearningAdenocarcinomaAnimalsApoptosisAutomationCell ProliferationFemaleHumansImage Processing, Computer-AssistedMagnetic Resonance ImagingMaleMiceMice, NudeProstatic NeoplasmsTumor Cells, Cultured

Identifiers

PMID32415137
PMCPMC7228927

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.