Evidence map›Paper›PMID 32415089›Full record

ArticleScientific reports2020

Intraovarian injection of mesenchymal stem cells improves oocyte yield and in vitro embryo production in a bovine model of fertility loss.

Patricia F Malard, Mauricio A S Peixer, Joao G Grazia, Hilana Dos Santos Sena Brunel, Luiz F Feres, Carla L Villarroel, Luiz G B Siqueira, Margot A N Dode, Robert Pogue, Joao Henrique M Viana and 1 more

Abstract read
In one paragraph

Article in Scientific reports, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Frontiers in veterinary science · 2025
    Article
  6. Review
  7. Article
  8. Article
  9. Review
  10. Article
  11. Review
  12. An Update on Applications of Cattle Mesenchymal Stromal Cells.Animals : an open access journal from MDPI · 2022
    Review
  13. Review
  14. Review
  15. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Patricia F MalardUniversidade Católica de Brasília, Brasília, DF, 70790-160, Brazil. patricia@biotecnologiaanimal.com.br.ORCID http://orcid.org/0000-0002-3073-4748
Mauricio A S PeixerUniversidade Católica de Brasília, Brasília, DF, 70790-160, Brazil.ORCID http://orcid.org/0000-0002-9118-7768
Joao G GraziaCenatte Embrioes, Pedro Leopoldo, MG, 33600-000, Brazil.ORCID http://orcid.org/0000-0002-9976-681X
Hilana Dos Santos Sena BrunelBio Biotecnologia da Reprodução Animal, Brasília, DF, 71735-505, Brazil.ORCID http://orcid.org/0000-0002-9425-1593
Luiz F FeresUniversidade de Alfenas, Alfenas, MG, 37132-440, Brazil.ORCID http://orcid.org/0000-0001-7566-2859
Carla L VillarroelBio Biotecnologia da Reprodução Animal, Brasília, DF, 71735-505, Brazil.ORCID http://orcid.org/0000-0002-5125-9798
Luiz G B SiqueiraEmpresa Brasileira de Pesquisa Agropecuária - EMBRAPA Gado de Leite, Juiz de Fora, MG, 36038-330, Brazil.ORCID http://orcid.org/0000-0002-2800-5829
Margot A N DodeEmpresa Brasileira de Pesquisa Agropecuária - EMBRAPA Recursos Genéticos e Biotecnologia, Brasília, DF, 70770-917, Brazil.ORCID http://orcid.org/0000-0002-1096-0457
Robert PogueUniversidade Católica de Brasília, Brasília, DF, 70790-160, Brazil.ORCID http://orcid.org/0000-0002-8789-3512
Joao Henrique M Viana *Empresa Brasileira de Pesquisa Agropecuária - EMBRAPA Recursos Genéticos e Biotecnologia, Brasília, DF, 70770-917, Brazil.ORCID http://orcid.org/0000-0002-3742-2368
Juliana L Carvalho *Universidade Católica de Brasília, Brasília, DF, 70790-160, Brazil. julianalott@gmail.com.ORCID http://orcid.org/0000-0002-1423-0523

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Valuable female cattle are continuously subject to follicular puncture (ovum pick-up - OPU). This technique is commonly used for in-vitro embryo production, but may result in ovarian lesion. Mesenchymal stem cells (MSC) ameliorate the function of injured tissues, but their use to treat ovarian lesions in cattle has not been established. We investigated whether a local injection of MSC would reduce the negative effects of repeated OPU under acute and chronic scenarios in bovines. First, we performed four OPU sessions and injected 2.5 × 10

Indexed as

Embryonic DevelopmentMesenchymal Stem CellsMesenchymal Stem Cell TransplantationAnimalsBiomarkersBlastocystCattleCell DifferentiationEmbryo Culture TechniquesEmbryo, MammalianFemaleFertilization in VitroGene Expression ProfilingInfertility, FemaleOocytesOvaryBiomarkers

Identifiers

PMID32415089
PMCPMC7229041

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.