Evidence map›Paper›PMID 32414944›Full record

ArticleESMO open2020

Prognostic impact of indoleamine 2,3-dioxygenase 1

Panagiota Economopoulou, Athina Kladi-Skandali, Areti Strati, George Koytsodontis, Efthymios Kirodimos, Evangelos Giotakis, Pavlos Maragoudakis, Eleni Gagari, Eirini Maratou, George Dimitriadis and 7 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in ESMO open, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed, 2 pooled it
5.8field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 2 syntheses or guidelines pooled it, 29 citations in OpenAlex.

  1. The immunotherapeutic role of indoleamine 2,3-dioxygenase in head and neck squamous cell carcinoma: A systematic review.Clinical otolaryngology : official journal of ENT-UK ; official journal of Netherlands Society for Oto-Rhino-Laryngology & Cervico-Facial Surgery · 2021
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors at 3 institutions in 2 countries.

Panagiota EconomopoulouSecond Department of Internal Medicine, Section of Medical Oncology, Attikon University Hospital, National and Kapodistrian University of Athens, Athens, Greece.
Athina Kladi-SkandaliSecond Department of Internal Medicine, Section of Medical Oncology, Attikon University Hospital, National and Kapodistrian University of Athens, Athens, Greece.
Areti StratiDepartment of Chemistry, National and Kapodistrian University of Athens, Athens, Greece.
George KoytsodontisSecond Department of Internal Medicine, Section of Medical Oncology, Attikon University Hospital, National and Kapodistrian University of Athens, Athens, Greece.
Efthymios KirodimosDepartment of Otolaryngology-Head and Neck Surgery, Hippokration General Hospital, National and Kapodistrian University of Athens, Athens, Greece.
Evangelos GiotakisDepartment of Otorhinolaryngology, Facial Plastic and Reconstructive Surgery, Städtisches Klinikum, Karlsruhe, Germany.
Pavlos MaragoudakisSecond Otolaryngology Department, Attikon University Hospital, National and Kapodistrian University of Athens, Athens, Greece.
Eleni GagariOral Medicine Clinics, A. Syggros Hospital of Dermatologic and Venereal Diseases, National and Kapodistrian University of Athens, Athens, Greece.
Eirini MaratouHellenic National Center for the Research, Prevention and Treatment of Diabetes Mellitus and its Complications (H.N.D.C), Athens, Greece.
George DimitriadisSecond Department of Internal Medicine and Research Institute, Faculty of Medicine, National and Kapodistrian University of Athens, Attikon University Hospital, Athens, Greece.
Ioannis KotsantisSecond Department of Internal Medicine, Section of Medical Oncology, Attikon University Hospital, National and Kapodistrian University of Athens, Athens, Greece.
Elena VagiaSecond Department of Internal Medicine, Section of Medical Oncology, Attikon University Hospital, National and Kapodistrian University of Athens, Athens, Greece.
Maria AnastasiouSecond Department of Internal Medicine, Section of Medical Oncology, Attikon University Hospital, National and Kapodistrian University of Athens, Athens, Greece.
Maria GkotzamanidouSecond Department of Internal Medicine, Section of Medical Oncology, Attikon University Hospital, National and Kapodistrian University of Athens, Athens, Greece.
George KavourakisSecond Department of Internal Medicine, Section of Medical Oncology, Attikon University Hospital, National and Kapodistrian University of Athens, Athens, Greece.
Evi LianidouDepartment of Chemistry, National and Kapodistrian University of Athens, Athens, Greece.
Amanda PsyrriSecond Department of Internal Medicine, Section of Medical Oncology, Attikon University Hospital, National and Kapodistrian University of Athens, Athens, Greece. Electronic address: psyrri237@yahoo.com.
National and Kapodistrian University of Athens · GRHellenic Center for Disease Control & Prevention · GRStädtisches Klinikum Karlsruhe · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundWe sought to determine the prognostic role of indoleamine 2,3-dioxygenase 1 (

methodsIn a prospective cohort of 113 patients with LA HNSCC, we evaluated expression of

results

conclusionsOur results strongly suggest that

Indexed as

Head and Neck NeoplasmsNeoplastic Cells, CirculatingHumansIndoleamine-Pyrrole 2,3,-DioxygenasePrognosisProspective StudiesRNA, MessengerSquamous Cell Carcinoma of Head and NeckIDO1 protein, humanIndoleamine-Pyrrole 2,3,-DioxygenaseRNA, Messengercell deathCTCshead and neck cancerIDO1

Identifiers

PMID32414944
PMCPMC7232623
OpenAlexW3025645364

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.