ArticleProceedings of the National Academy of Sciences of the United States of America2020
Host nutrient milieu drives an essential role for aspartate biosynthesis during invasive
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In one paragraph
Article in Proceedings of the National Academy of Sciences of the United States of America, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 55 papers.
0numbers the graph read from it
0cells of the map it votes in
55citing papers in PubMed
1.0field-weighted citation impact, top 13% of its field
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
55 citing papers in PubMed, 68 citations in OpenAlex.
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- Overcoming methicillin resistance in Staphylococcus aureus via metal ion disruption of bacterial metabolism.npj antimicrobials and resistance · 2026Article
- Profiling of genetic determinants required for fitness of community-associated methicillin-resistantMicrobiology spectrum · 2026Article
- Aspartate aminotransferase is required forInfection and immunity · 2026Article
- The cellular esterase FrmB controls metabolic homeostasis and small colony variant formation inbioRxiv : the preprint server for biology · 2026Article
- Integrated multi-omics reveals coordinatedmSystems · 2026Article
- The osteoclast intracellular environment fosters bacterial growth duringbioRxiv : the preprint server for biology · 2026Article
- Aspartate aminotransferase is required forbioRxiv : the preprint server for biology · 2026Article
- Article
- The β-lactam adjuvant guanosine potentiates anti-folate antibiotics and pyrimidine synthesis inhibitors by depleting thymidine in methicillin-resistantbioRxiv : the preprint server for biology · 2026Article
- Proteomic and metabolomic profiling of methicillin-resistantFrontiers in microbiology · 2026Article
- Article
- Defects in anaplerotic metabolism sensitizeMicrobiology spectrum · 2025Article
- Environmental cues in different host niches shape the survival fitness of Staphylococcus aureus.Nature communications · 2025Article
- Metabolic Master Switch: Pyruvate Carboxylase Fuels Antimicrobial Resistance and Virulence in FoodborneFoods (Basel, Switzerland) · 2025Article
- The nucleobase analog 4-thiouracil hijacks the pyrimidine salvage pathway to inhibitMicrobiology spectrum · 2025Article
- Review
- Regulatory dynamics of arginine metabolism in Staphylococcus aureus.Biochemical Society transactions · 2024Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors at 2 institutions in 1 country.
Aimee D PotterDepartment of Pathology, Microbiology, and Immunology, Vanderbilt University Medical Center, Nashville, TN 37232.ORCID 0000-0003-1473-1149
Casey E ButricoDepartment of Pathology, Microbiology, and Immunology, Vanderbilt University Medical Center, Nashville, TN 37232.ORCID 0000-0002-8236-7281
Caleb A FordDepartment of Biomedical Engineering, Vanderbilt University, Nashville, TN 37235.ORCID 0000-0002-3710-8037
Jacob M CurryDivision of Pediatric Infectious Diseases, Department of Pediatrics, Vanderbilt University Medical Center, Nashville, TN 37232.ORCID 0000-0002-9242-0461
Irina A TrenaryDepartment of Chemical and Biomolecular Engineering, Vanderbilt University, Nashville, TN 37235.
Srivarun S TummarakotaDepartment of Pathology, Microbiology, and Immunology, Vanderbilt University Medical Center, Nashville, TN 37232.
Andrew S HendrixDivision of Pediatric Infectious Diseases, Department of Pediatrics, Vanderbilt University Medical Center, Nashville, TN 37232.
Jamey D YoungDepartment of Chemical and Biomolecular Engineering, Vanderbilt University, Nashville, TN 37235.ORCID 0000-0002-0871-1494
James E CassatDepartment of Pathology, Microbiology, and Immunology, Vanderbilt University Medical Center, Nashville, TN 37232; jim.cassat@vumc.org.ORCID 0000-0002-1199-1167
Vanderbilt University Medical Center · USVanderbilt University · US
Funding
MEDICAL SCIENTIST TRAINING PROGRAMT32GM007347 · NIGMS · VANDERBILT UNIVERSITY · PI WILLIAMS, CHRISTOPHER S. · 1985 to 2023
$26.3MMedical Scientist Training ProgramT32GM152284 · NIGMS · VANDERBILT UNIVERSITY · PI Christopher S. Williams · 2024 to 2026
$4.8MDefining the impact of host factors on the molecular architecture and bacterial physiology of Staphylococcus aureus abscessesR01AI145992 · NIAID · VANDERBILT UNIVERSITY MEDICAL CENTER · PI CASSAT, JAMES E, SKAAR, ERIC P · 2020 to 2024
$3.8MThe impact of hypoxia on Staphylococcus aureus metabolism and virulence during osteomyelitisR01AI132560 · NIAID · VANDERBILT UNIVERSITY MEDICAL CENTER · PI CASSAT, JAMES E · 2017 to 2021
$1.9MIn Vivo 2H/13C Metabolic Flux Analysis of NASH PathogenesisR01DK106348 · NIDDK · VANDERBILT UNIVERSITY · PI YOUNG, JAMEY D. · 2015 to 2019
$1.7MTools for Leveraging High-Resolution MS Detection of Stable Isotope Enrichments to Upgrade the Information Content of Metabolomics DatasetsU01CA235508 · NCI · VANDERBILT UNIVERSITY · PI ALLEN, DOUG, YOUNG, JAMEY D. · 2018 to 2021
$1.7MHost-pathogen interactions during osteomyelitisK08AI113107 · NIAID · VANDERBILT UNIVERSITY MEDICAL CENTER · PI CASSAT, JAMES E · 2014 to 2018
$885kThe impact of host hypoxic signaling on antibacterial immunity and bone repair during Staphylococcus aureus osteomyelitisF30AI138424 · NIAID · VANDERBILT UNIVERSITY · PI FORD, CALEB ANTHONY · 2018 to 2022
$120kThe Skeletal Environment Dictates Staphylococcus aureus Virulence and Metabolic ProcessesF31AI133970 · NIAID · VANDERBILT UNIVERSITY · PI POTTER, AIMEE · 2017 to 2018
$58kNCI NIH HHS U01 CA235508NIAID NIH HHS F30 AI138424NIAID NIH HHS F31 AI133970NIAID NIH HHS K08 AI113107NIAID NIH HHS R01 AI132560NIAID NIH HHS R01 AI145992NIDDK NIH HHS R01 DK106348NIGMS NIH HHS T32 GM007347NIGMS NIH HHS T32 GM152284
Abstract
The bacterial pathogen
Indexed as
AnimalsAspartic AcidDisease Models, AnimalFemaleHumansMiceMice, Inbred C57BLNutrientsOsteomyelitisStaphylococcal InfectionsStaphylococcus aureusAspartic AcidNutrientsaspartatemetabolismosteomyelitispathogenesisStaphylococcus aureus
Identifiers
What OpenQuestion holds
Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390
Registered trials
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.