Evidence map›Paper›PMID 32414911›Full record

ArticleThe Journal of biological chemistry2020

Forcing the ribosome to change its message.

Sarah E Leininger, Carol Deutsch, Edward P O'Brien

Abstract readComment
In one paragraph

Article in The Journal of biological chemistry, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

3 authors.

Sarah E LeiningerDepartment of Chemistry, Pennsylvania State University, University Park, Pennsylvania 16802.
Carol DeutschDepartment of Physiology, University of Pennsylvania, Philadelphia, Pennsylvania 19104 cjd@pennmedicine.upenn.edu.ORCID 0000-0003-1475-5562
Edward P O'BrienDepartment of Chemistry, Pennsylvania State University, University Park, Pennsylvania 16802 epo2@psu.edu.

Funding

FUNCTION AND ASSEMBLY OF POTASSIUM CHANNELSR01GM052302 · NIGMS · UNIVERSITY OF PENNSYLVANIA · PI DEUTSCH, CAROL J · 1995 to 2024
$13.4M
Translation Kinetics and their Effects on Protein Structure and Function, mRNA half-lives, and Cellular PhenotypeR35GM124818 · NIGMS · PENNSYLVANIA STATE UNIVERSITY, THE · PI Edward Patrick O'Brien · 2017 to 2026
$4.0M
NIGMS NIH HHS R01 GM052302NIGMS NIH HHS R35 GM124818
6 · The paper itself

Abstract

Mechanical forces can be generated when nascent protein segments are integrated into a membrane. These forces are then transmitted through the nascent protein to the ribosome's catalytic core, but only a few biological consequences of this process have been identified to date. In this issue, Harrington

Indexed as

AlphavirusFrameshifting, RibosomalPolyproteinsProteinsRibosomesPolyproteinsProteins

Identifiers

PMID32414911
PMCPMC7242706

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.