Evidence map›Paper›PMID 32414902›Full record

ArticleAJNR. American journal of neuroradiology2020

A Critical Assessment of the Golden Hour and the Impact of Procedural Timing in Stroke Thrombectomy.

A P Wessell, H D P Carvalho, E Le, G Cannarsa, M J Kole, J A Stokum, T Chryssikos, T R Miller, S Chaturvedi, D Gandhi and 3 more

Open access · hybridAbstract read
In one paragraph

Article in AJNR. American journal of neuroradiology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 1 pooled it
0.7field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 1 synthesis or guideline pooled it, 17 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 5 institutions in 1 country.

A P WessellDepartments of Neurosurgery (A.P.W., G.C., M.J.K., J.A.S., T.C.) apwessell@gmail.com.ORCID 0000-0001-5268-1061
H D P CarvalhoFrom the Division of Interventional Neuroradiology (H.D.P.C., E.L., T.R.M., D.G., G.J.).ORCID 0000-0003-1563-7963
E LeFrom the Division of Interventional Neuroradiology (H.D.P.C., E.L., T.R.M., D.G., G.J.).ORCID 0000-0002-5783-7034
G CannarsaDepartments of Neurosurgery (A.P.W., G.C., M.J.K., J.A.S., T.C.).ORCID 0000-0003-0728-511X
M J KoleDepartments of Neurosurgery (A.P.W., G.C., M.J.K., J.A.S., T.C.).ORCID 0000-0003-0446-2547
J A StokumDepartments of Neurosurgery (A.P.W., G.C., M.J.K., J.A.S., T.C.).ORCID 0000-0002-8547-9334
T ChryssikosDepartments of Neurosurgery (A.P.W., G.C., M.J.K., J.A.S., T.C.).ORCID 0000-0003-4550-4125
T R MillerFrom the Division of Interventional Neuroradiology (H.D.P.C., E.L., T.R.M., D.G., G.J.).ORCID 0000-0003-4115-8536
S ChaturvediNeurology (S.C., K.Y.), University of Maryland Medical Center, Baltimore, Maryland.ORCID 0000-0001-8660-7644
D GandhiFrom the Division of Interventional Neuroradiology (H.D.P.C., E.L., T.R.M., D.G., G.J.).ORCID 0000-0001-6741-5970
K YarbroughNeurology (S.C., K.Y.), University of Maryland Medical Center, Baltimore, Maryland.ORCID 0000-0002-7853-3996
S R SattiDepartment of Neurointerventional Surgery (S.R.S.), Christiana Care Health System, Newark, Delaware.ORCID 0000-0001-6671-7918
G JindalFrom the Division of Interventional Neuroradiology (H.D.P.C., E.L., T.R.M., D.G., G.J.).ORCID 0000-0002-2124-902X
Society of Interventional Radiology · USAnna Needs Neuroblastoma Answers · USUniversity of Maryland, Baltimore · USChristiana Care Health System · USMACOM (United States) · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

background and purposePrevious studies in acute ischemic stroke have demonstrated the importance of minimizing delays to endovascular treatment and keeping thrombectomy procedural times at <30-60 minutes. The purpose of this study was to investigate the impact of thrombectomy procedural times on clinical outcomes. MATERIALS AND

methodsWe retrospectively compared 319 patients having undergone thrombectomy according to procedural time (<30 minutes, 30-60 minutes, and >60 minutes) and time from stroke onset to endovascular therapy (≤6 or >6 hours). Clinical characteristics of patients with postprocedural intracranial hemorrhage were also assessed. Logistic regression was used to determine independent predictors of poor outcome at 90 days (mRS ≥3).

resultsGreater age (OR, 1.03; 95% CI, 1.01-1.06;

conclusionsThrombectomy procedural times beyond 60 minutes are associated with lower revascularization rates and worse 90-day outcomes. Procedural time itself was not an independent predictor of outcome. While stroke thrombectomy procedures should be performed rapidly, our study emphasizes the significance of achieving revascularization despite the requisite procedural time. However, the potential for revascularization must be weighed against the risks associated with multiple thrombectomy attempts.

Indexed as

Time-to-TreatmentAgedAged, 80 and overBrain IschemiaEndovascular ProceduresFemaleHumansMaleMiddle AgedRetrospective StudiesStrokeThrombectomyTreatment Outcome

Identifiers

PMID32414902
PMCPMC7228171
OpenAlexW3024654063

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.