Evidence map›Paper›PMID 32414887›Full record

ArticleDiabetes care2020

Natural Language Processing Improves Detection of Nonsevere Hypoglycemia in Medical Records Versus Coding Alone in Patients With Type 2 Diabetes but Does Not Improve Prediction of Severe Hypoglycemia Events: An Analysis Using the Electronic Medical Record in a Large Health System.

Anita D Misra-Hebert, Alex Milinovich, Alex Zajichek, Xinge Ji, Todd D Hobbs, Wayne Weng, Paul Petraro, Sheldon X Kong, Michelle Mocarski, Rahul Ganguly and 4 more

Open access · bronzeAbstract read
In one paragraph

Article in Diabetes care, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 2 pooled it
1.1field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 2 syntheses or guidelines pooled it, 12 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Article
  4. Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 3 institutions in 1 country.

Anita D Misra-HebertDepartment of Internal Medicine and Center for Value-Based Care Research, Cleveland Clinic Community Care, Cleveland Clinic, Cleveland, OH misraa@ccf.org.ORCID 0000-0003-3079-7025
Alex MilinovichDepartment of Quantitative Health Sciences, Lerner Research Institute, Cleveland Clinic, Cleveland, OH.
Alex ZajichekDepartment of Quantitative Health Sciences, Lerner Research Institute, Cleveland Clinic, Cleveland, OH.
Xinge JiDepartment of Quantitative Health Sciences, Lerner Research Institute, Cleveland Clinic, Cleveland, OH.
Todd D HobbsNovo Nordisk, Inc., Plainsboro, NJ.
Wayne WengNovo Nordisk, Inc., Plainsboro, NJ.ORCID 0000-0002-1427-426X
Paul PetraroNovo Nordisk, Inc., Plainsboro, NJ.
Sheldon X KongNovo Nordisk, Inc., Plainsboro, NJ.
Michelle MocarskiNovo Nordisk, Inc., Plainsboro, NJ.
Rahul GangulyNovo Nordisk, Inc., Plainsboro, NJ.
Janine M BaumanDepartment of Quantitative Health Sciences, Lerner Research Institute, Cleveland Clinic, Cleveland, OH.
Kevin M PantaloneDepartment of Endocrinology, Endocrinology & Metabolism Institute, Cleveland Clinic, Cleveland, OH.
Robert S ZimmermanDepartment of Endocrinology, Endocrinology & Metabolism Institute, Cleveland Clinic, Cleveland, OH.
Michael W KattanDepartment of Quantitative Health Sciences, Lerner Research Institute, Cleveland Clinic, Cleveland, OH.
Novo Nordisk (United States) · USCleveland Clinic Lerner College of Medicine · USCleveland Clinic · US

Funding

Impact of a Team-based Approach to Primary Care: A Natural Experiment in Primary Care RedesignK08HS024128 · AHRQ · CLEVELAND CLINIC FOUNDATION · PI MISRA-HEBERT, ANITA DIANA · 2016 to 2020
$738k
AHRQ HHS K08 HS024128
6 · The paper itself

Abstract

objectiveTo determine if natural language processing (NLP) improves detection of nonsevere hypoglycemia (NSH) in patients with type 2 diabetes and no NSH documentation by diagnosis codes and to measure if NLP detection improves the prediction of future severe hypoglycemia (SH). RESEARCH DESIGN AND

methodsFrom 2005 to 2017, we identified NSH events by diagnosis codes and NLP. We then built an SH prediction model.

resultsThere were 204,517 patients with type 2 diabetes and no diagnosis codes for NSH. Evidence of NSH was found in 7,035 (3.4%) of patients using NLP. We reviewed 1,200 of the NLP-detected NSH notes and confirmed 93% to have NSH. The SH prediction model (C-statistic 0.806) showed increased risk with NSH (hazard ratio 4.44;

conclusionsDetection of NSH improved with NLP in patients with type 2 diabetes without improving SH prediction.

Indexed as

AlgorithmsInternational Classification of DiseasesNatural Language ProcessingAdultAgedAged, 80 and overClinical Decision RulesCommunity Health PlanningDiabetes Mellitus, Type 2Electronic Health RecordsFemaleHumansHypoglycemiaInformation Storage and RetrievalMaleMiddle Aged

Identifiers

PMID32414887
PMCPMC7372042
OpenAlexW3025251476

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.