Evidence map›Paper›PMID 32414868›Full record

ArticleGenetics2020

Biased Gene Conversion Constrains Adaptation in

Tuomas Hämälä, Peter Tiffin

Open access · bronzeAbstract read
In one paragraph

Article in Genetics, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
3.4field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 33 citations in OpenAlex.

  1. Article
  2. ThebioRxiv : the preprint server for biology · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Tuomas HämäläDepartment of Plant and Microbial Biology, University of Minnesota, St. Paul, Minnesota 55108 thamala@umn.edu.ORCID 0000-0001-8306-3397
Peter TiffinDepartment of Plant and Microbial Biology, University of Minnesota, St. Paul, Minnesota 55108.ORCID 0000-0003-1975-610X
University of Minnesota · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Reduction of fitness due to deleterious mutations imposes a limit to adaptive evolution. By characterizing features that influence this genetic load we may better understand constraints on responses to both natural and human-mediated selection. Here, using whole-genome, transcriptome, and methylome data from >600

Indexed as

Adaptation, PhysiologicalEvolution, MolecularGene ConversionArabidopsisArabidopsis ProteinsEpigenomeGenetic FitnessGenome, PlantMutationSelection, GeneticTranscriptomeArabidopsis ProteinsArabidopsisbiased gene conversiondeleterious mutationsDFE-alphaevolutionary simulationsmachine-learning

Identifiers

PMID32414868
PMCPMC7337087
OpenAlexW3024309490

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.