Evidence map›Paper›PMID 32414800›Full record

ArticleApplied and environmental microbiology2020

Antimicrobial Peptide GH12 Prevents Dental Caries by Regulating Dental Plaque Microbiota.

Wentao Jiang, Yufei Wang, Junyuan Luo, Xiangshu Chen, Yuhao Zeng, Xinwei Li, Zening Feng, Linglin Zhang

Open access · greenAbstract read
In one paragraph

Article in Applied and environmental microbiology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
2.0field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 34 citations in OpenAlex.

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  12. Isolation of Thermophilic BacteriaInternational journal of dentistry · 2024
    Article
  13. Review
  14. Article
  15. Article
  16. Novel antimicrobial agents targeting theFrontiers in cellular and infection microbiology · 2022
    Review
  17. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Wentao Jiang *State Key Laboratory of Oral Diseases & National Clinical Research Centre for Oral Disease, Sichuan University, Chengdu, China.
Yufei Wang *State Key Laboratory of Oral Diseases & National Clinical Research Centre for Oral Disease, Sichuan University, Chengdu, China.
Junyuan LuoState Key Laboratory of Oral Diseases & National Clinical Research Centre for Oral Disease, Sichuan University, Chengdu, China.
Xiangshu ChenState Key Laboratory of Oral Diseases & National Clinical Research Centre for Oral Disease, Sichuan University, Chengdu, China.
Yuhao ZengState Key Laboratory of Oral Diseases & National Clinical Research Centre for Oral Disease, Sichuan University, Chengdu, China.
Xinwei LiState Key Laboratory of Oral Diseases & National Clinical Research Centre for Oral Disease, Sichuan University, Chengdu, China.
Zening FengState Key Laboratory of Oral Diseases & National Clinical Research Centre for Oral Disease, Sichuan University, Chengdu, China.
Linglin ZhangState Key Laboratory of Oral Diseases & National Clinical Research Centre for Oral Disease, Sichuan University, Chengdu, China zhll_sc@163.com.
Sichuan University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Due to the complex microecology and microenvironment of dental plaque, novel caries prevention strategies require modulating the microbial communities ecologically and reducing the cariogenic properties effectively. Antimicrobial peptide GH12 reduced the lactic acid production and exopolysaccharide (EPS) synthesis of a

Indexed as

AdultAnimalsAnti-Bacterial AgentsAntimicrobial Cationic PeptidesBacterial Physiological PhenomenaBiofilmsDental CariesDental PlaqueFemaleHumansMaleMicrobiotaRatsRats, Sprague-DawleySpecific Pathogen-Free OrganismsYoung AdultAnti-Bacterial AgentsAntimicrobial Cationic Peptidesantimicrobial peptidesbiofilmsdental cariesdental plaquemicrobiota

Identifiers

PMID32414800
PMCPMC7357485
OpenAlexW3025730071

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.