Evidence map›Paper›PMID 32414784›Full record

ArticleThe Journal of neuroscience : the official journal of the Society for Neuroscience2020

TRPM4 Conductances in Thalamic Reticular Nucleus Neurons Generate Persistent Firing during Slow Oscillations.

John J O'Malley, Frederik Seibt, Jeannie Chin, Michael Beierlein

Open access · bronzeAbstract read
In one paragraph

Article in The Journal of neuroscience : the official journal of the Society for Neuroscience, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
1.6field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 17 citations in OpenAlex.

  1. Article
  2. Article
  3. TREK1 Channels Shape Spindle-Like Oscillations, Neuronal Activity, and Short-Term Synaptic Plasticity in Thalamocortical Circuits.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2025
    Article
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  6. Review
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  10. Review
  11. IInternational journal of molecular sciences · 2021
    Article
  12. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 1 country.

John J O'MalleyDepartment of Neurobiology & Anatomy, McGovern Medical School at UTHealth, Houston, Texas 77030.ORCID 0000-0003-3774-1702
Frederik SeibtDepartment of Neurobiology & Anatomy, McGovern Medical School at UTHealth, Houston, Texas 77030.ORCID 0000-0003-0536-5212
Jeannie ChinDepartment of Neuroscience, Baylor College of Medicine, Houston, Texas 77030.ORCID 0000-0001-9902-3744
Michael BeierleinDepartment of Neurobiology & Anatomy, McGovern Medical School at UTHealth, Houston, Texas 77030 michael.beierlein@uth.tmc.edu.ORCID 0000-0003-2210-3118
The University of Texas MD Anderson Cancer Center · USBaylor College of Medicine · USThe University of Texas Health Science Center · US

Funding

Role of deltaFosB in hippocampal gene expression and function in neurological diseaseR01NS085171 · NINDS · THOMAS JEFFERSON UNIVERSITY · PI CHIN, JEANNIE · 2014 to 2022
$4.4M
Thalamic Reticular Nucleus Dysfunction in Alzheimer's DiseaseR01AG065290 · NIA · BAYLOR COLLEGE OF MEDICINE · PI BEIERLEIN, MICHAEL, CHIN, JEANNIE · 2020 to 2024
$3.5M
Accelerated depletion of hippocampal neural stem cells in neurological diseaseR01NS086965 · NINDS · THOMAS JEFFERSON UNIVERSITY · PI CHIN, JEANNIE · 2014 to 2018
$2.0M
Synaptic Integration in Neurons of the Thalamic Reticular NucleusR01NS077989 · NINDS · UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON · PI BEIERLEIN, MICHAEL · 2012 to 2016
$1.6M
NIA NIH HHS R01 AG065290NINDS NIH HHS R01 NS077989NINDS NIH HHS R01 NS085171NINDS NIH HHS R01 NS086965
6 · The paper itself

Abstract

During sleep, neurons in the thalamic reticular nucleus (TRN) participate in distinct types of oscillatory activity. While the reciprocal synaptic circuits between TRN and sensory relay nuclei are known to underlie the generation of sleep spindles, the mechanisms regulating slow (<1 Hz) forms of thalamic oscillations are not well understood. Under

Indexed as

Action PotentialsAnimalsFemaleGABAergic NeuronsIntralaminar Thalamic NucleiMaleMiceMice, Inbred C57BLNeural PathwaysOrgan Culture TechniquesSleepTRPM Cation ChannelsTRPM4 protein, mouseTRPM Cation Channelsoscillationpersistent activitythalamic reticular nucleusthalamocorticalTRPM4T-type

Identifiers

PMID32414784
PMCPMC7326353
OpenAlexW3025065382

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.