Evidence map›Paper›PMID 32414780›Full record

ArticleScience (New York, N.Y.)2020

Inferring change points in the spread of COVID-19 reveals the effectiveness of interventions.

Jonas Dehning, Johannes Zierenberg, F Paul Spitzner, Michael Wibral, Joao Pinheiro Neto, Michael Wilczek, Viola Priesemann

Abstract read
In one paragraph

Article in Science (New York, N.Y.), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 370 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
370citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

370 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Trial
  4. Article
  5. Optimizing infectious disease mitigation under dynamic conditions.Proceedings of the National Academy of Sciences of the United States of America · 2026
    Article
  6. Mechanics of pandemics.EClinicalMedicine · 2026
    Review
  7. Article
  8. Article
  9. Article
  10. Observational
  11. Review
  12. Article
  13. Article
  14. Data assimilation for estimating time-varying reproduction numbers.Journal of the Royal Society, Interface · 2025
    Article
  15. Review
  16. How Will AI Shape the Future of Pandemic Response? Early Clues From Data Analytics.Risk analysis : an official publication of the Society for Risk Analysis · 2025
    Review
  17. Article
  18. Article
  19. Article
  20. Article

310 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Jonas Dehning *Max Planck Institute for Dynamics and Self-Organization, 37077 Göttingen, Germany.ORCID 0000-0002-1728-2505
Johannes Zierenberg *Max Planck Institute for Dynamics and Self-Organization, 37077 Göttingen, Germany.ORCID 0000-0001-5840-3791
F Paul Spitzner *Max Planck Institute for Dynamics and Self-Organization, 37077 Göttingen, Germany.ORCID 0000-0001-9774-4572
Michael WibralCampus Institute for Dynamics of Biological Networks, University of Göttingen, 37075 Göttingen, Germany.ORCID 0000-0001-8010-5862
Joao Pinheiro NetoMax Planck Institute for Dynamics and Self-Organization, 37077 Göttingen, Germany.ORCID 0000-0003-3027-8276
Michael Wilczek *Max Planck Institute for Dynamics and Self-Organization, 37077 Göttingen, Germany.
Viola Priesemann *Max Planck Institute for Dynamics and Self-Organization, 37077 Göttingen, Germany. viola.priesemann@ds.mpg.de.ORCID 0000-0001-8905-5873

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

As coronavirus disease 2019 (COVID-19) is rapidly spreading across the globe, short-term modeling forecasts provide time-critical information for decisions on containment and mitigation strategies. A major challenge for short-term forecasts is the assessment of key epidemiological parameters and how they change when first interventions show an effect. By combining an established epidemiological model with Bayesian inference, we analyzed the time dependence of the effective growth rate of new infections. Focusing on COVID-19 spread in Germany, we detected change points in the effective growth rate that correlate well with the times of publicly announced interventions. Thereby, we could quantify the effect of interventions and incorporate the corresponding change points into forecasts of future scenarios and case numbers. Our code is freely available and can be readily adapted to any country or region.

Indexed as

Bayes TheoremCoronavirus InfectionsCOVID-19COVID-19 Drug TreatmentForecastingGermanyHumansPandemicsPneumonia, Viral

Identifiers

PMID32414780
PMCPMC7239331

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.