Evidence map›Paper›PMID 32414744›Full record

ReviewEuropean respiratory review : an official journal of the European Respiratory Society2020

Prognostic factors in chronic hypersensitivity pneumonitis.

Andrew W Creamer, Shaney L Barratt

Open access · diamondAbstract readReview
In one paragraph

Review in European respiratory review : an official journal of the European Respiratory Society, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 1 pooled it
2.8field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 1 synthesis or guideline pooled it, 42 citations in OpenAlex.

  1. Prognostic biomarkers for the development of progressive pulmonary fibrosis in hypersensitivity pneumonitis: a systematic review.European respiratory review : an official journal of the European Respiratory Society · 2025
    Pooled it
  2. Review
  3. Article
  4. Unveiling the role of circulating periostin in patients with idiopathic pulmonary fibrosis: A prognostic meta-analysis.Sarcoidosis, vasculitis, and diffuse lung diseases : official journal of WASOG · 2025
    Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Occupational hypersensitivity pneumonia.Tuberkuloz ve toraks · 2023
    Review
  10. Progressive fibrotic interstitial lung disease.Jornal brasileiro de pneumologia : publicacao oficial da Sociedade Brasileira de Pneumologia e Tisilogia · 2023
    Article
  11. Review
  12. Article
  13. Chronic hypersensitivity pneumonitis; an enigmatic and frequently fatal disease.European respiratory review : an official journal of the European Respiratory Society · 2020
    Article
  14. HyperpolarizedRespiratory medicine
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Andrew W CreamerBristol Interstitial Lung Disease Service, Southmead Hospital, North Bristol NHS Trust, Bristol, UK andrew.creamer@nhs.net.ORCID https://orcid.org/0000-0002-9314-1210
Shaney L BarrattBristol Interstitial Lung Disease Service, Southmead Hospital, North Bristol NHS Trust, Bristol, UK.ORCID https://orcid.org/0000-0003-3067-7349
North Bristol NHS Trust · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Hypersensitivity pneumonitis (HP) is an immunologically mediated lung disease resulting from exposure to inhaled environmental antigens. Prognosis is variable, with a subset of patients developing progressive fibrosis leading to respiratory failure and death. Therefore, there is an urgent need to identify factors which predict prognosis and survival in patients with HP. We undertook a narrative review of existing evidence to identify prognostic factors in patients with chronic HP. Patient demographics, smoking history, extent of antigen exposure and comorbidities all have reported associations with disease outcome, and physiological, radiological and laboratory markers have been shown to predict overall survival. While no single marker has been demonstrated to accurately and reliably predict prognosis, older age, more severe impairment of pulmonary function at baseline and established fibrosis on either biopsy or high-resolution computed tomography are consistently associated with worse survival. The vast majority of existing studies are retrospective, and this review identifies a need for prospective longitudinal studies with serial assessment of respiratory health to ascertain factors associated with nonfatal deterioration. Future developments, including the development of HP-specific composite scores may help further improve our ability to predict outcomes for individual patients.

Indexed as

AdultAgedAlveolitis, Extrinsic AllergicAntigensChronic DiseaseComorbidityEnvironmental ExposureFemaleGenetic Predisposition to DiseaseHumansMaleMiddle AgedPrognosisPulmonary AlveoliRisk AssessmentRisk FactorsAntigens

Identifiers

PMID32414744
PMCPMC9489027
OpenAlexW3025483427

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.