Evidence map›Paper›PMID 32414606›Full record

ArticleJournal of autoimmunity2020

Tracking immunodynamics by identification of S-G

Miguel Muñoz-Ruiz, Irma Pujol-Autonell, Hefin Rhys, Heather M Long, Maria Greco, Mark Peakman, Tim Tree, Adrian C Hayday, Francesca Di Rosa

Open access · hybridAbstract read
In one paragraph

Article in Journal of autoimmunity, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
1.1field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 17 citations in OpenAlex.

  1. TCF1bioRxiv : the preprint server for biology · 2026
    Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. COVID-19: Using high-throughput flow cytometry to dissect clinical heterogeneity.Cytometry. Part A : the journal of the International Society for Analytical Cytology · 2023
    Review
  7. Article
  8. Low-dose IL-2 reduces IL-21Nature communications · 2022
    Article
  9. Review
  10. OMIP-079: Cell cycle of CD4Cytometry. Part A : the journal of the International Society for Analytical Cytology · 2021
    Article
  11. Article
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 2 countries.

Miguel Muñoz-RuizImmunosurveillance Laboratory, The Francis Crick Institute, London, UK.
Irma Pujol-AutonellPeter Gorer Department of Immunobiology, King's College London, London, UK; National Institute for Health Research (NIHR) Biomedical Research Center (BRC), Guy's and St Thomas' NHS Foundation Trust and King's College London, London, UK.
Hefin RhysFlow Cytometry Science Technology Platform, The Francis Crick Institute, London, UK.
Heather M LongInstitute of Immunology and Immunotherapy, University of Birmingham, Birmingham, UK.
Maria GrecoGenomics Equipment Park, The Francis Crick Institute, London, UK.
Mark PeakmanPeter Gorer Department of Immunobiology, King's College London, London, UK; National Institute for Health Research (NIHR) Biomedical Research Center (BRC), Guy's and St Thomas' NHS Foundation Trust and King's College London, London, UK.
Tim TreePeter Gorer Department of Immunobiology, King's College London, London, UK; National Institute for Health Research (NIHR) Biomedical Research Center (BRC), Guy's and St Thomas' NHS Foundation Trust and King's College London, London, UK.
Adrian C HaydayImmunosurveillance Laboratory, The Francis Crick Institute, London, UK; Peter Gorer Department of Immunobiology, King's College London, London, UK; National Institute for Health Research (NIHR) Biomedical Research Center (BRC), Guy's and St Thomas' NHS Foundation Trust and King's College London, London, UK.
Francesca Di RosaImmunosurveillance Laboratory, The Francis Crick Institute, London, UK; Peter Gorer Department of Immunobiology, King's College London, London, UK; Institute of Molecular Biology and Pathology, National Research Council of Italy (CNR), Rome, Italy. Electronic address: francesca.dirosa@cnr.it.
King's College London · GBThe Francis Crick Institute · GBUniversity of Birmingham · GB

Funding

Cancer Research UK 20265Department of HealthMedical Research CouncilWellcome TrustWellcome Trust FC001003
6 · The paper itself

Abstract

The ready availability of human blood makes it the first choice for immuno-monitoring. However, this has been largely confined to static metrics, particularly resting T cell phenotypes. Conversely, dynamic assessments have mostly relied on cell stimulation in vitro which is subject to multiple variables. Here, immunodynamic insights from the peripheral blood are shown to be obtainable by applying a revised approach to cell-cycle analysis. Specifically, refined flow cytometric protocols were employed, assuring the reliable quantification of T cells in the S-G

Indexed as

AnimalsCell Cycle CheckpointsFlow CytometryHumansMiceMice, TransgenicMonitoring, ImmunologicT-LymphocytesCD8 T cellsImmuno-monitoringType 1 diabetes

Identifiers

PMID32414606
PMCPMC7527781
OpenAlexW3025492365

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.