ArticleIntensive & critical care nursing2020
Factors associated with ABCDE bundle adherence in critically ill adults requiring mechanical ventilation: An observational design.
Article in Intensive & critical care nursing, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
6 citing papers in PubMed.
- Ethnic Disparities in Deep Sedation of Patients with Acute Respiratory Distress Syndrome in the United States: Secondary Analysis of a Multicenter Randomized Trial.Annals of the American Thoracic Society · 2024Trial
- Improving resident physicians' knowledge of the ABCDEF bundle through a multimodal teaching intervention.International journal of medical education · 2025Article
- Effect of educational program on nurses' performance regarding application of liberation bundle in pediatric intensive care unit.BMC nursing · 2025Article
- Dexmedetomidine for postoperative delirium in surgical patients: a mini-review of mechanisms, clinical evidence, and practical implementation.Frontiers in pharmacology · 2025Review
- Patient, Practice, and Organizational Factors Associated With Early Mobility Performance in Critically Ill Adults.American journal of critical care : an official publication, American Association of Critical-Care Nurses · 2024Article
- Improving Outcomes in Mechanically Ventilated Adult ICU Patients Following Implementation of the ICU Liberation (ABCDEF) Bundle Across a Large Healthcare System.Critical care explorations · 2024Article
Corrections and comments
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Authors and funding
5 authors.
Funding
Abstract
objectiveTo identify factors associated with the ABCDEF bundle (Assess, prevent, and manage pain, Both, spontaneous awakening and breathing trials, Choice of sedation/analgesia, Delirium assess, prevent and manage, Early mobility/exercise and Family engagement/empowerment) adherence, in critically ill patients during the first 96 hours of mechanical ventilation.
designObservational study using electronic health record data.
setting15 intensive care units located in seven community hospitals in a western United States health system. PATIENTS: 977 adult patients who were on mechanical ventilation for greater than 24 hours and admitted to an intensive care unit over six months. MEASUREMENTS AND MAIN
resultsMultiple regression analysis was used to examine factors contributing to bundle adherence while adjusting for severity of illness, days on mechanical ventilation, hospital site and time elapsed. ABCDEF bundle adherence was higher in patients on mechanical ventilation for less than 48 hours (p = 0.01), who received continuous sedation for less than 24 hours (p < 0.001), admitted from skilled nursing facilities (p < 0.05), and over the course of the six-month study period (p < 0.01). Bundle adherence was significantly lower for Hispanic patients (p < 0.01).
conclusionsOur study identified potentially modifiable factors that could improve the team's performance of the ABCDEF bundle in patients requiring mechanical ventilation.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.