ReviewTrends in neurosciences2020
Transitions in Brain Evolution: Space, Time and Entropy.
Review in Trends in neurosciences, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
11 citing papers in PubMed.
- Fish welfare in a changing world: New developments and current challenges.Journal of fish biology · 2026Review
- Molecular Basis Underlying Changes of Brain Entropy and Couplings in Late-life Depression.Current neuropharmacology · 2026Article
- Irruption and Absorption: A 'Black-Box' Framework for How Mind and Matter Make a Difference to Each Other.Entropy (Basel, Switzerland) · 2024Article
- Irruption Theory: A Novel Conceptualization of the Enactive Account of Motivated Activity.Entropy (Basel, Switzerland) · 2023Article
- Control systems theory revisited: new insights on the brain clocks of time-to-action.Frontiers in neuroscience · 2023Article
- Basal metabolic rate and risk of multiple sclerosis: a Mendelian randomization study.Metabolic brain disease · 2022Article
- Arrow of Time, Entropy, and Protein Folding: Holistic View on Biochirality.International journal of molecular sciences · 2022Review
- Entropy for the Brain and Applied Computation.Entropy (Basel, Switzerland) · 2021Article
- Action Video Gaming Experience Related to Altered Resting-State EEG Temporal and Spatial Complexity.Frontiers in human neuroscience · 2021Article
- Entropy and the Brain: An Overview.Entropy (Basel, Switzerland) · 2020Review
- An Evolutionary Perspective of Dyslexia, Stress, and Brain Network Homeostasis.Frontiers in human neuroscience · 2020Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
Abstract
How did brains evolve to become so complex, and what is their future? Brains pose an explanatory challenge because entropy, which inexorably increases over time, is commonly associated with disorder and simplicity. Recently we showed how evolution is an entropic process, building structures - organisms - which themselves facilitate entropy growth. Here we suggest that key transitional points in evolution extended organisms' reach into space and time, opening channels into new regions of a complex multidimensional state space that also allow entropy to increase. Brain evolution enabled representation of space and time, which vastly enhances this process. Some of these channels lead to tiny, dead-ends in the state space: the persistence of complex life is thus not thermodynamically guaranteed.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.