Evidence map›Paper›PMID 32414242›Full record

ArticleThe Journal of chemical physics2020

SABRE polarized low field rare-spin spectroscopy.

Sören Lehmkuhl, Martin Suefke, Arne Kentner, Yi-Fen Yen, Bernhard Blümich, Matthew S Rosen, Stephan Appelt, Thomas Theis

Abstract read
In one paragraph

Article in The Journal of chemical physics, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed.

  1. Article
  2. Journal of the American Chemical Society · 2026
    Article
  3. Article
  4. Ultra-low fieldCommunications chemistry · 2026
    Article
  5. Article
  6. Article
  7. Article
  8. Analytical chemistry · 2023
    Article
  9. Article
  10. Article
  11. Spin dynamics of [1,2-Physical chemistry chemical physics : PCCP · 2023
    Article
  12. Review
  13. An open-source, low-cost NMR spectrometer operating in the mT field regime.Journal of magnetic resonance (San Diego, Calif. : 1997) · 2021
    Article
  14. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Sören LehmkuhlDepartment of Chemistry, North Carolina State University, 851 Main Campus Dr, Raleigh, North Carolina 27606, USA.ORCID 0000000213217677
Martin SuefkeInstitute of Energy and Climate Research (IEK-9), Forschungszentrum Jülich GmbH, 52425 Jülich, Germany.ORCID 0000000193013465
Arne KentnerInstitute of Technical and Macromolecular Chemistry, RWTH Aachen University, Worringerweg 2, 52056 Aachen, Germany.
Yi-Fen YenMartinos Center for Biomedical Imaging, Massachusetts General Hospital, Boston, Massachusetts 02129, USA.ORCID 0000000199865327
Bernhard BlümichInstitute of Technical and Macromolecular Chemistry, RWTH Aachen University, Worringerweg 2, 52056 Aachen, Germany.ORCID 0000000211524438
Matthew S RosenMartinos Center for Biomedical Imaging, Massachusetts General Hospital, Boston, Massachusetts 02129, USA.ORCID 000000027194002X
Stephan AppeltInstitute of Energy and Climate Research (IEK-9), Forschungszentrum Jülich GmbH, 52425 Jülich, Germany.ORCID 0000000160362167
Thomas TheisDepartment of Chemistry, North Carolina State University, 851 Main Campus Dr, Raleigh, North Carolina 27606, USA.ORCID 0000000167799978

Funding

Molecular imaging with a hyperpolarized Vitamin ShotR21EB025313 · NIBIB · NORTH CAROLINA STATE UNIVERSITY RALEIGH · PI THEIS, THOMAS · 2018 to 2019
$661k
NIBIB NIH HHS R21 EB025313
6 · The paper itself

Abstract

High-field nuclear magnetic resonance (NMR) spectroscopy is an indispensable technique for identification and characterization of chemicals and biomolecular structures. In the vast majority of NMR experiments, nuclear spin polarization arises from thermalization in multi-Tesla magnetic fields produced by superconducting magnets. In contrast, NMR instruments operating at low magnetic fields are emerging as a compact, inexpensive, and highly accessible alternative but suffer from low thermal polarization at a low field strength and consequently a low signal. However, certain hyperpolarization techniques create high polarization levels on target molecules independent of magnetic fields, giving low-field NMR a significant sensitivity boost. In this study, SABRE (Signal Amplification By Reversible Exchange) was combined with high homogeneity electromagnets operating at mT fields, enabling high resolution

Identifiers

PMID32414242
PMCPMC7228779

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.