ArticleInternational journal of environmental research and public health2020
Multimorbidity among Two Million Adults in China.
Article in International journal of environmental research and public health, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers, 2 of them syntheses that pooled it.
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
33 citing papers in PubMed, 2 syntheses or guidelines pooled it, 53 citations in OpenAlex.
- A systematic review and meta-analysis of disease clusters in multimorbidity.Nature communications · 2025Pooled it
- Social determinants of multimorbidity patterns: A systematic review.Frontiers in public health · 2023Pooled it
- Age-period-cohort analysis of multimorbidity prevalence among Chinese older adults: from 2002 to 2022.GeroScience · 2026Article
- Association between air pollution exposure and multimorbidity among middle-aged and older adults in China: a cross-sectional study.Scientific reports · 2026Article
- U-shaped association between hemoglobin levels and cardiometabolic multimorbidity in older adults: a large-scale cross-sectional study.BMC geriatrics · 2026Article
- Identification of Six Potential Therapeutic Targets Common to Ischemic Stroke and Vascular Dementia: Genetic Insights From an Integrated Bioinformatics Analysis.Brain and behavior · 2025Article
- Multimorbidity and Depressive Symptoms and their Association with Self-Reported Health and Life Satisfaction Among Adults Aged ≥ 50 Years in Mexico.Journal of cross-cultural gerontology · 2025Article
- Article
- Self-reported health as a predictor of cardiometabolic multimorbidity in Chinese older adults: a national cross-sectional study.Frontiers in public health · 2025Article
- An unsupervised cluster analysis of multimorbidity patterns in older adults in Shenzhen, China.Frontiers in public health · 2025Article
- Analysis of the current situation and factors influencing the utilization of somatic and somatic-mental disorder comorbidity and health services among middle-aged and older adult people in China.Frontiers in public health · 2025Article
- Potential diagnostic value of circulating miRNAs in HFrEF and bioinformatics analysis.Heliyon · 2024Article
- The diabetes mellitus multimorbidity network in hospitalized patients over 50 years of age in China: data mining of medical records.BMC public health · 2024Article
- Learning prevalent patterns of co-morbidities in multichronic patients using population-based healthcare data.Scientific reports · 2024Article
- Prevalence and pattern of multimorbidity in China: a cross-sectional study of 224,142 adults over 60 years old.Frontiers in public health · 2024Article
- Novel approaches to glaucomatous neurodegeneration, based on the integrated stress response.Molecular therapy. Nucleic acids · 2023Article
- Global and regional prevalence of multimorbidity in the adult population in community settings: a systematic review and meta-analysis.EClinicalMedicine · 2023Article
- Identification of status quo and association rules for chronic comorbidity among Chinese middle-aged and older adults rural residents.Frontiers in public health · 2023Article
- Prevalence of common chronic disease and multimorbidity patterns in Guangdong province with three typical cultures: analysis of data from the Diverse Life-Course Cohort study.Frontiers in public health · 2023Article
- Associated adverse health outcomes of polypharmacy and potentially inappropriate medications in community-dwelling older adults with diabetes.Frontiers in pharmacology · 2023Article
Corrections and comments
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Authors and funding
10 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
To explore the multimorbidity prevalence and patterns among middle-aged and older adults from China. Data on thirteen chronic diseases were collected from 2,097,150 participants aged over 45 years between January 1st 2011 and December 31st 2015 from Beijing Medical Claim Data for Employees. Association rule mining and hierarchical cluster analysis were applied to assess multimorbidity patterns. Multimorbidity prevalence was 51.6% and 81.3% in the middle-aged and older groups, respectively. The most prevalent disease pair was that of osteoarthritis and rheumatoid arthritis (OARA) with hypertension (HT) (middle-aged: 22.5%; older: 41.8%). Ischaemic heart disease (IHD), HT, and OARA constituted the most common triad combination (middle-aged: 11.0%; older: 31.2%). Among the middle-aged group, the strongest associations were found in a combination of cerebrovascular disease (CBD), OARA, and HT with IHD in males (lift = 3.49), and CBD, OARA, and COPD with IHD in females (lift = 3.24). Among older patients, glaucoma and cataracts in females (lift = 2.95), and IHD, OARA, and glaucoma combined with cataracts in males (lift = 2.45) were observed. Visual impairment clusters, a mixed cluster of OARA, IHD, COPD, and cardiometabolic clusters were detected. Multimorbidity is prevalent among middle-aged and older Chinese individuals. The observations of multimorbidity patterns have implications for improving preventive care and developing appropriate guidelines for morbidity treatment.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.