ArticleCancers2020
Identification of Distinct Heterogenic Subtypes and Molecular Signatures Associated with African Ancestry in Triple Negative Breast Cancer Using Quantified Genetic Ancestry Models in Admixed Race Populations.
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Article in Cancers, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
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20citing papers in PubMed
1.9field-weighted citation impact, top 13% of its field
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Who cites it
20 citing papers in PubMed, 43 citations in OpenAlex.
- SOMATIC MUTATION PROFILES IN COLORECTAL CANCERS DIFFER BY POPULATION.medRxiv : the preprint server for health sciences · 2026Article
- Unveiling Disparities: Analyzing Hispanic Inclusion in Liver Cancer Research Databases in the United States.Journal of racial and ethnic health disparities · 2025Article
- 3D In Vitro Models of Breast Cancer: Current Challenges and Future Prospects Toward Recapitulating the Microenvironment and Mimicking Key Processes.Advanced biology · 2025Review
- Race-related host and microbe transcriptomic signatures in triple-negative breast cancer.NPJ breast cancer · 2025Article
- Article
- African Genetic Ancestry, Structural and Social Determinants of Health, and Mortality in Black Adults.JAMA network open · 2025Article
- Spatial localization of collagen hydroxylated proline site variation as an ancestral trait in the breast cancer microenvironment.Matrix biology : journal of the International Society for Matrix Biology · 2025Article
- Kinome-Focused CRISPR-Cas9 Screens in African Ancestry Patient-Derived Breast Cancer Organoids Identify Essential Kinases and Synergy of EGFR and FGFR1 Inhibition.Cancer research · 2025Article
- The DARC side of genetics in cancer: Breast cancer disparities.American journal of human genetics · 2024Article
- Response to: Comment on Genetic Ancestry-Specific Molecular and Survival Differences in Admixed Breast Cancer Patients.Annals of surgery open : perspectives of surgical history, education, and clinical approaches · 2024Article
- Neighborhood Disadvantage and Breast Cancer-Specific Survival in the US.JAMA network open · 2024Article
- The Anticancer Effects of Marine Carotenoid Fucoxanthin through Phosphatidylinositol 3-Kinase (PI3K)-AKT Signaling on Triple-Negative Breast Cancer Cells.Molecules (Basel, Switzerland) · 2023Article
- Racial Disparities in Breast Cancer Treatments and Adverse Events in the SEER-Medicare Data.Cancers · 2023Article
- Neighborhood Disadvantage, African Genetic Ancestry, Cancer Subtype, and Mortality Among Breast Cancer Survivors.JAMA network open · 2023Article
- African Ancestry-Associated Gene Expression Profiles in Triple-Negative Breast Cancer Underlie Altered Tumor Biology and Clinical Outcome in Women of African Descent.Cancer discovery · 2022Article
- Analysis of the genomic landscapes of Barbadian and Nigerian women with triple negative breast cancer.Cancer causes & control : CCC · 2022Article
- Breast cancer disparities in outcomes; unmasking biological determinants associated with racial and genetic diversity.Clinical & experimental metastasis · 2022Review
- Cancer microenvironment and genomics: evolution in process.Clinical & experimental metastasis · 2022Review
- Article
- Kaiso (ZBTB33) subcellular partitioning functionally links LC3A/B, the tumor microenvironment, and breast cancer survival.Communications biology · 2021Article
Corrections and comments
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Authors and funding
18 authors at 5 institutions in 2 countries.
Melissa DavisDepartment of Surgery, Weill Cornell Medicine, New York, NY 10065, USA.ORCID 0000-0002-6124-6923
Rachel MartiniDepartment of Surgery, Weill Cornell Medicine, New York, NY 10065, USA.
Lisa NewmanDepartment of Surgery, Weill Cornell Medicine, New York, NY 10065, USA.
Olivier ElementoDepartment of Physiology and Biophysics, Weill Cornell Medicine, New York, NY 10065, USA.
Jason WhiteDepartment of Biology and Center for Cancer Research, Tuskegee University, Tuskegee, AL 36088, USA.
Akanksha VermaDepartment of Computational Biology, Weill Cornell Medicine, New York, NY 10065, USA.
Indrani DattaDepartment of Public Health Sciences, Henry Ford Health System, Detroit, MI 48202, USA.
Indra AdriantoDepartment of Public Health Sciences, Henry Ford Health System, Detroit, MI 48202, USA.
Yalei ChenDepartment of Public Health Sciences, Henry Ford Health System, Detroit, MI 48202, USA.
Kevin GardnerDepartment of Pathology and Cell Biology, Columbia University, New York, NY 10027, USA.
Hyung-Gyoon KimDepartment of Pathology, University of Alabama at Birmingham, Birmingham, AL 35233, USA.
Windy D ColombDepartment of Biology and Center for Cancer Research, Tuskegee University, Tuskegee, AL 36088, USA.
Isam-Eldin EltoumDepartment of Pathology, University of Alabama at Birmingham, Birmingham, AL 35233, USA.
Andra R FrostDepartment of Pathology, University of Alabama at Birmingham, Birmingham, AL 35233, USA.
William E GrizzleDepartment of Pathology, University of Alabama at Birmingham, Birmingham, AL 35233, USA.
Andrea SbonerCaryl and Israel Englander Institute for Precision Medicine, Weill Cornell Medicine, New York, NY 10065, USA.
Upender ManneDepartment of Pathology, University of Alabama at Birmingham, Birmingham, AL 35233, USA.
Clayton YatesDepartment of Biology and Center for Cancer Research, Tuskegee University, Tuskegee, AL 36088, USA.ORCID 0000-0001-5420-9852
Cornell University · USUniversity of Alabama at Birmingham · USCenter for Cancer Research · USHenry Ford Health System · USColumbia University · US
Funding
XRAY CRYSTALLOGRAPHYP30CA013148 · NCI · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI Robert S Welner · 1985 to 2026
$165.9MTuskegee University Center for Biomedical Research/ Research Centers at Minority InstitutionsU54MD007585 · NIMHD · TUSKEGEE UNIVERSITY · PI Jason Anthony White · 2017 to 2026
$29.4MTRAINING AND CAREER DEVELOPMENTU54CA118948 · NCI · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI UPENDER MANNE · 2005 to 2026
$26.6MResearch Education CoreU54CA118623 · NCI · TUSKEGEE UNIVERSITY · PI Vivian L Carter, TIMOTHY TURNER · 2005 to 2026
$20.2MProject 3: Physical and Metabolic Constraints of Cancer Cell InvasionU54CA210184 · NCI · CORNELL UNIVERSITY · PI CANTLEY, LEWIS C., FISCHBACH, CLAUDIA · 2016 to 2020
$10.2MThe DARC side of Breast CancerR21CA210237 · NCI · UNIVERSITY OF GEORGIA · PI DAVIS, MELISSA B · 2017 to 2018
$386kNCI NIH HHS 5U54CA118948NCI NIH HHS P30 CA013148NCI NIH HHS P30CA013148NCI NIH HHS R21 CA210237NCI NIH HHS U54 CA118623NCI NIH HHS U54 CA210184NIMHD NIH HHS L60 MD002419NIMHD NIH HHS U54-MD007585-26U.S. Department of Defense PC170315P1, W81XWH-18-1-0589
Abstract
Triple negative breast cancers (TNBCs) are molecularly heterogeneous, and the link between their aggressiveness with African ancestry is not established. We investigated primary TNBCs for gene expression among self-reported race (SRR) groups of African American (AA,
Indexed as
African ancestrydisparitiesoncologic pathwaysRNAseq analysistriple negative breast cancer
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