Evidence map›Paper›PMID 32414052›Full record

ArticleMolecules (Basel, Switzerland)2020

PET Imaging of [

Naresh Damuka, Paul W Czoty, Ashley T Davis, Michael A Nader, Susan H Nader, Suzanne Craft, Shannon L Macauley, Lindsey K Galbo, Phillip M Epperly, Christopher T Whitlow and 5 more

Open access · goldAbstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
1.3field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 18 citations in OpenAlex.

  1. Article
  2. Imaging Microtubule Dynamics In Vivo in Human Brain: Optimal Quantification Based on a Test-Retest Study.Journal of nuclear medicine : official publication, Society of Nuclear Medicine · 2026
    Article
  3. Imaging microtubule dynamics: A new frontier in biomarker development for neurodegenerative diseases.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2025
    Review
  4. Article
  5. Article
  6. Development and Optimization ofACS pharmacology & translational science · 2023
    Review
  7. Article
  8. Binding Parameters of [Pharmaceuticals (Basel, Switzerland) · 2023
    Article
  9. [Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie · 2022
    Article
  10. Article
  11. Article
  12. Effect of ethanol and cocaine on [Molecular biology reports · 2021
    Article
  13. Review
  14. Preliminary Evaluations of [Frontiers in neuroscience · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 2 institutions in 1 country.

Naresh DamukaDepartment of Radiology, Wake Forest School of Medicine, Winston-Salem, NC 27157, USA.
Paul W CzotyDepartment of Physiology and Pharmacology, Wake Forest School of Medicine, Winston-Salem, NC 27157, USA.
Ashley T DavisDepartment of Radiology, Wake Forest School of Medicine, Winston-Salem, NC 27157, USA.
Michael A NaderDepartment of Radiology, Wake Forest School of Medicine, Winston-Salem, NC 27157, USA.ORCID 0000-0001-5704-0247
Susan H NaderDepartment of Physiology and Pharmacology, Wake Forest School of Medicine, Winston-Salem, NC 27157, USA.
Suzanne CraftDepartment of Internal Medicine-Gerontology, Wake Forest School of Medicine, Winston-Salem, NC 27157, USA.
Shannon L MacauleyDepartment of Internal Medicine-Gerontology, Wake Forest School of Medicine, Winston-Salem, NC 27157, USA.
Lindsey K GalboDepartment of Physiology and Pharmacology, Wake Forest School of Medicine, Winston-Salem, NC 27157, USA.ORCID 0000-0001-8672-8323
Phillip M EpperlyDepartment of Physiology and Pharmacology, Wake Forest School of Medicine, Winston-Salem, NC 27157, USA.
Christopher T WhitlowDepartment of Radiology, Wake Forest School of Medicine, Winston-Salem, NC 27157, USA.
April T DavenportDepartment of Physiology and Pharmacology, Wake Forest School of Medicine, Winston-Salem, NC 27157, USA.
Thomas J MartinDepartment of Anesthesiology, Wake Forest School of Medicine, Winston-Salem, NC 27157, USA.ORCID 0000-0003-2800-5308
James B DaunaisDepartment of Physiology and Pharmacology, Wake Forest School of Medicine, Winston-Salem, NC 27157, USA.
Akiva MintzDepartment of Radiology, Columbia University, New York, NY 10016, USA.
Kiran Kumar Solingapuram SaiDepartment of Radiology, Wake Forest School of Medicine, Winston-Salem, NC 27157, USA.ORCID 0000-0002-6442-5169
Wake Forest University · USColumbia University · US

Funding

Wake Forest Clinical and Translational Science AwardUL1TR001420 · NCATS · WAKE FOREST UNIVERSITY HEALTH SCIENCES · PI ARD, JAMY D, FOLEY, KRISTIE L · 2015 to 2023
$32.3M
Wake Forest Translational Alcohol Research Center (WF-TARC)P50AA026117 · NIAAA · WAKE FOREST UNIVERSITY HEALTH SCIENCES · PI Jeffrey L. Weiner · 2018 to 2026
$16.2M
Wake Forest Alzheimer's Disease Core CenterP30AG049638 · NIA · WAKE FOREST UNIVERSITY HEALTH SCIENCES · PI WILLIAMSON, JEFF DOUGLAS · 2016 to 2020
$12.2M
Mechanisms Mediating Cocaine Abuse in Socially Housed Female and Male MonkeysR01DA017763 · NIDA · WAKE FOREST UNIVERSITY HEALTH SCIENCES · PI Michael A Nader · 2004 to 2026
$9.8M
The metabolic interplay of sleep and Alzheimer's diseaseR01AG068330 · NIA · WAKE FOREST UNIVERSITY HEALTH SCIENCES · PI MACAULEY-RAMBACH, SHANNON L · 2020 to 2024
$3.5M
Evaluating microtubule binding as a potential imaging biomarker for Alzheimer's diseaseR01AG065839 · NIA · WAKE FOREST UNIVERSITY HEALTH SCIENCES · PI SOLINGAPURAM SAI, KIRAN · 2020 to 2024
$2.5M
NIA NIH HHS P30 AG049638NIA NIH HHS R01 AG065839NIA NIH HHS R01 AG068330NIH HHS P50AA026117NIH HHS P50DA006634-27NIH HHS R01AG065839-01NIH HHS R01 DA017763
6 · The paper itself

Abstract

Dysregulation of microtubules is commonly associated with several psychiatric and neurological disorders, including addiction and Alzheimer's disease. Imaging of microtubules in vivo using positron emission tomography (PET) could provide valuable information on their role in the development of disease pathogenesis and aid in improving therapeutic regimens. We developed [

Indexed as

BrainCarbon RadioisotopesPositron-Emission TomographyAnimalsMacaca fascicularisMaleMicrotubulesQuinazolinesRadiopharmaceuticalsCarbon RadioisotopesQuinazolinesRadiopharmaceuticalsverubulinblood–brain barriermicrotubulenon-human primatePET imagingreproducibility

Identifiers

PMID32414052
PMCPMC7287733
OpenAlexW3024042106

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.