ArticlePractical radiation oncology
Differences in the Patterns of Failure Between IROC Lung and Spine Phantom Irradiations.
Article in Practical radiation oncology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
14 citing papers in PubMed, 1 synthesis or guideline pooled it, 25 citations in OpenAlex.
- AAPM MEDICAL PHYSICS PRACTICE GUIDELINE 5.b: Commissioning and QA of treatment planning dose calculations-Megavoltage photon and electron beams.Journal of applied clinical medical physics · 2022Guideline
- Radiation Therapy Quality Assurance Analysis of Alliance A021501: Preoperative mFOLFIRINOX or mFOLFIRINOX Plus Hypofractionated Radiation Therapy for Borderline Resectable Adenocarcinoma of the Pancreas.International journal of radiation oncology, biology, physics · 2024Trial
- The radiotherapy quality assurance gap among phase III cancer clinical trials.Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology · 2022Trial
- Development of a cost-effective end-to-end commissioning test for simulation-omitted direct-to-unit adaptive radiotherapy.Physics and imaging in radiation oncology · 2026Article
- A novel audit methodology to improve detection of planning and delivery errors in passive motion management.Physics and imaging in radiation oncology · 2026Article
- Trends and Challenges: A 15-Year Review of Imaging and Radiation Oncology Core Anthropomorphic Phantom Audits for Proton Therapy.International journal of particle therapy · 2026Article
- Comprehensive end-to-end dosimetry audit for stereotactic body radiotherapy in spine, lung, and soft tissue.Journal of applied clinical medical physics · 2025Article
- Design and validation of a novel dosimetry phantom for motion management audits.Journal of applied clinical medical physics · 2025Article
- Early results of a remote dosimetry audit program for lung stereotactic body radiation therapy.Physics and imaging in radiation oncology · 2024Article
- Analysis of Performance and Failure Modes of the IROC Proton Liver Phantom.International journal of particle therapy · 2023Article
- Adoption of respiratory motion management in radiation therapy.Physics and imaging in radiation oncology · 2022Article
- Photon beam modeling variations predict errors in IMRT dosimetry audits.Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology · 2022Article
- Dose calculation errors as a component of failing IROC lung and spine phantom irradiations.Medical physics · 2020Article
- Failure Modes in IROC Photon Liver Phantom Irradiations.Practical radiation oncologyArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors at 2 institutions in 1 country.
Funding
Abstract
purposeOur purpose was to investigate and classify the reasons why institutions fail the Imaging and Radiation Oncology Core (IROC) stereotactic body radiation therapy (SBRT) spine and moving lung phantoms, which are used to credential institutions for clinical trial participation. METHODS AND MATERIALS: All IROC moving lung and SBRT spine phantom irradiation failures recorded from January 2012 to December 2018 were evaluated in this study. A failure was a case where the institution did not meet the established IROC criteria for agreement between planned and delivered dose. We analyzed the reports for all failing irradiations, including point dose disagreement, dose profiles, and gamma analyses. Classes of failure patterns were created and used to categorize each instance.
resultsThere were 158 failing cases analyzed: 116 of 1052 total lung irradiations and 42 of 263 total spine irradiations. Seven categories were required to describe the lung phantom failures, whereas 4 were required for the spine. Types of errors present in both phantom groups included systematic dose and localization errors. Fifty percent of lung failures were due to a superior-inferior localization error, that is, error in the direction of major motion. Systematic dose errors, however, contributed to only 22% of lung failures. In contrast, the majority (60%) of spine phantom failures were due to systematic dose errors, with localization errors (in any direction) accounting for only 14% of failures.
conclusionsThere were 2 distinct patterns of failure between the IROC moving lung and SBRT spine phantoms. The majority of the lung phantom failures were due to localization errors, whereas the spine phantom failures were largely attributed to systematic dose errors. Both of these errors are clinically relevant and could manifest as errors in patient cases. These findings highlight the value of independent end-to-end dosimetry audits and can help guide the community in improving the quality of radiation therapy by focusing attention on where errors manifest in the community.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.