Evidence map›Paper›PMID 32412926›Full record

ReviewExercise and sport sciences reviews2020

Synergy between Acute Intermittent Hypoxia and Task-Specific Training.

Joseph F Welch, Tommy W Sutor, Alicia K Vose, Raphael R Perim, Emily J Fox, Gordon S Mitchell

Registry-linked trialOpen access · greenAbstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Exercise and sport sciences reviews, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06520358 (Acute Intermittent Hypoxia to Improve Airway Protection in Chronic Traumatic Brain Injury), which is not on this map. Cited by 16 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed, 1 pooled it
2.2field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06520358 nacompletednot on this mapstarted 2024, after this paper: background citation

Acute Intermittent Hypoxia to Improve Airway Protection in Chronic Traumatic Brain Injury

TypeinterventionalSponsorUniversity of FloridaRan2024 to 2025Enrolled5ConditionsTraumatic Brain InjuryArmsAcute Intermittent Hypoxia (AIH), Task specific Airway Protection Training, Sham AIH
3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 1 synthesis or guideline pooled it, 32 citations in OpenAlex.

  1. Acute intermittent hypoxia in spinal cord injury gait rehabilitation: a systematic review of randomized trials.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2025
    Pooled it
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  7. Intermittent hypoxia: a call for harmonization in terminology.Journal of applied physiology (Bethesda, Md. : 1985) · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Joseph F WelchCenter for Respiratory Research and Rehabilitation, Department of Physical Therapy, University of Florida, Gainesville, FL.
Tommy W SutorCenter for Respiratory Research and Rehabilitation, Department of Physical Therapy, University of Florida, Gainesville, FL.
Alicia K VoseCenter for Respiratory Research and Rehabilitation, Department of Physical Therapy, University of Florida, Gainesville, FL.
Raphael R PerimCenter for Respiratory Research and Rehabilitation, Department of Physical Therapy, University of Florida, Gainesville, FL.
Emily J Fox
Gordon S MitchellCenter for Respiratory Research and Rehabilitation, Department of Physical Therapy, University of Florida, Gainesville, FL.
University of Florida · US

Funding

Functional mapping of peripheral and central circuits for airway protection and breathingOT2OD023854 · OD · UNIVERSITY OF FLORIDA · PI BOLSER, DONALD C · 2016 to 2020
$10.8M
Optimizing respiratory plasticity with chronic cervical SCIR01HL147554 · NHLBI · UNIVERSITY OF FLORIDA · PI MITCHELL, GORDON S. · 2019 to 2022
$2.9M
NHLBI NIH HHS R01 HL147554NIH HHS OT2 OD023854
6 · The paper itself

Abstract

Acute intermittent hypoxia (AIH) and task-specific training (TST) synergistically improve motor function after spinal cord injury; however, mechanisms underlying this synergistic relation are unknown. We propose a hypothetical working model of neural network and cellular elements to explain AIH-TST synergy. Our goal is to forecast experiments necessary to advance our understanding and optimize the neurotherapeutic potential of AIH-TST.

Indexed as

Brain-Derived Neurotrophic FactorExercise TherapyHippocampusHumansHypoxiaMembrane GlycoproteinsMotor NeuronsNeuronal PlasticityReceptor, trkBSpinal CordSpinal Cord InjuriesBrain-Derived Neurotrophic FactorMembrane GlycoproteinsReceptor, trkBtropomyosin-related kinase-B, human

Identifiers

PMID32412926
PMCPMC7416561
OpenAlexW3025161111

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.