Evidence map›Paper›PMID 32412631›Full record

Observational studyEuropean heart journal2020

Reduction of hospitalizations for myocardial infarction in Italy in the COVID-19 era.

Salvatore De Rosa, Carmen Spaccarotella, Cristina Basso, Maria Pia Calabrò, Antonio Curcio, Pasquale Perrone Filardi, Massimo Mancone, Giuseppe Mercuro, Saverio Muscoli, Savina Nodari and 4 more

Erratum issuedOpen access · bronzeAbstract readMulticenter StudyObservational Study
In one paragraph

Observational study in European heart journal, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 546 papers, 5 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
546citing papers in PubMed, 5 pooled it
127.4field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

546 citing papers in PubMed, 5 syntheses or guidelines pooled it, 943 citations in OpenAlex.

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  15. Temporal trends and regional disparities in mortality from acute myocardial infarction in Brazil: a time series study, 2015-2024.Epidemiologia e servicos de saude : revista do Sistema Unico de Saude do Brasil · 2026
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  19. Drivers and recent trends of hospitalisation costs related to acute pulmonary embolism.Clinical research in cardiology : official journal of the German Cardiac Society · 2025
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486 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

14 authors at 10 institutions in 1 country.

Salvatore De RosaItalian Society of Cardiology, Via Po 24, 00198 Rome, Italy.
Carmen SpaccarotellaItalian Society of Cardiology, Via Po 24, 00198 Rome, Italy.
Cristina BassoItalian Society of Cardiology, Via Po 24, 00198 Rome, Italy.
Maria Pia CalabròItalian Society of Cardiology, Via Po 24, 00198 Rome, Italy.
Antonio CurcioItalian Society of Cardiology, Via Po 24, 00198 Rome, Italy.
Pasquale Perrone FilardiItalian Society of Cardiology, Via Po 24, 00198 Rome, Italy.
Massimo ManconeItalian Society of Cardiology, Via Po 24, 00198 Rome, Italy.
Giuseppe MercuroItalian Society of Cardiology, Via Po 24, 00198 Rome, Italy.
Saverio MuscoliItalian Society of Cardiology, Via Po 24, 00198 Rome, Italy.
Savina NodariItalian Society of Cardiology, Via Po 24, 00198 Rome, Italy.
Roberto PedrinelliItalian Society of Cardiology, Via Po 24, 00198 Rome, Italy.
Gianfranco SinagraItalian Society of Cardiology, Via Po 24, 00198 Rome, Italy.
Ciro IndolfiItalian Society of Cardiology, Via Po 24, 00198 Rome, Italy.
Società Italiana di Cardiologia and the CCU Academy investigators group
Magna Graecia University · ITSapienza University of Rome · ITUniversity of Trieste · ITUniversity of Messina · ITAzienda Socio Sanitaria Territoriale degli Spedali Civili di Brescia · ITUniversity of Cagliari · ITUniversity of Pisa · ITClinica Mediterranea · ITUniversity of Padua · ITUniversity of Rome Tor Vergata · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimsTo evaluate the impact of the COVID-19 pandemic on patient admissions to Italian cardiac care units (CCUs). METHODS AND

resultsWe conducted a multicentre, observational, nationwide survey to collect data on admissions for acute myocardial infarction (AMI) at Italian CCUs throughout a 1 week period during the COVID-19 outbreak, compared with the equivalent week in 2019. We observed a 48.4% reduction in admissions for AMI compared with the equivalent week in 2019 (P < 0.001). The reduction was significant for both ST-segment elevation myocardial infarction [STEMI; 26.5%, 95% confidence interval (CI) 21.7-32.3; P = 0.009] and non-STEMI (NSTEMI; 65.1%, 95% CI 60.3-70.3; P < 0.001). Among STEMIs, the reduction was higher for women (41.2%; P = 0.011) than men (17.8%; P = 0.191). A similar reduction in AMI admissions was registered in North Italy (52.1%), Central Italy (59.3%), and South Italy (52.1%). The STEMI case fatality rate during the pandemic was substantially increased compared with 2019 [risk ratio (RR) = 3.3, 95% CI 1.7-6.6; P < 0.001]. A parallel increase in complications was also registered (RR = 1.8, 95% CI 1.1-2.8; P = 0.009).

conclusionAdmissions for AMI were significantly reduced during the COVID-19 pandemic across Italy, with a parallel increase in fatality and complication rates. This constitutes a serious social issue, demanding attention by the scientific and healthcare communities and public regulatory agencies.

Indexed as

BetacoronavirusCoronavirus InfectionsMyocardial InfarctionPandemicsPneumonia, ViralAgedAged, 80 and overCOVID-19FemaleHospitalizationHumansItalyMaleMiddle AgedSARS-CoV-2Acute myocardial infarctionCardiac care unitsCOVID-19SARS-CoV2STEMI

Identifiers

PMID32412631
PMCPMC7239145
OpenAlexW3024307699

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.