Evidence map›Paper›PMID 32412629›Full record

Trial reportThe Journal of nutrition2020

The Intervention Nurses Start Infants Growing on Healthy Trajectories (INSIGHT) Responsive Parenting Intervention for Firstborns Affects Dietary Intake of Secondborn Infants.

Emily E Hohman, Jennifer S Savage, Leann L Birch, Ian M Paul

Registry-linked trialOpen access · greenAbstract readRandomized Controlled Trial
In one paragraph

Trial report in The Journal of nutrition, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT01167270 (The Intervention Nurses Start Infants Growing on Healthy Trajectories), which is not on this map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.1field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT01167270 nacompletednot on this map

The Intervention Nurses Start Infants Growing on Healthy Trajectories (INSIGHT) Study

TypeinterventionalSponsorIan M. Paul, MDRan2012 to 2023Enrolled316ConditionsInfant, ObesityArmsChild Safety Insights, Parenting Insights
3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 10 citations in OpenAlex.

  1. Article
  2. Methylation profiles at birth linked to early childhood obesity.Journal of developmental origins of health and disease · 2024
    Article
  3. Methylation profiles at birth linked to early childhood obesity.medRxiv : the preprint server for health sciences · 2024
    Article
  4. Article
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 1 country.

Emily E HohmanCenter for Childhood Obesity Research, Pennsylvania State University, University Park, PA, USA.
Jennifer S SavageCenter for Childhood Obesity Research, Pennsylvania State University, University Park, PA, USA.
Leann L BirchDepartment of Foods and Nutrition, University of Georgia, Athens, GA, USA.
Ian M PaulDepartments of Pediatrics and Public Health Sciences, Penn State College of Medicine, Hershey, PA, USA.
Pennsylvania State University · USPenn State Milton S. Hershey Medical Center · USUniversity of Georgia · US

Funding

Penn State Clinical and Translational Science InstituteUL1TR002014 · NCATS · PENNSYLVANIA STATE UNIV HERSHEY MED CTR · PI KRASCHNEWSKI, JENNIFER L. · 2016 to 2025
$33.7M
Preventing Obesity through Intervention during InfancyR01DK088244 · NIDDK · PENNSYLVANIA STATE UNIV HERSHEY MED CTR · PI PAUL, IAN M, WILLIAMS, JENNIFER SAVAGE · 2011 to 2022
$7.0M
Effect of Birth Order and Genetics on Infant Parenting and Obesity RiskR01DK099364 · NIDDK · PENNSYLVANIA STATE UNIV HERSHEY MED CTR · PI PAUL, IAN M · 2013 to 2017
$3.1M
NCATS NIH HHS UL1 TR002014NIDDK NIH HHS R01 DK088244NIDDK NIH HHS R01 DK099364
6 · The paper itself

Abstract

backgroundAlthough previous work has shown that children with older siblings tend to have poorer diet quality, no study has directly compared diets of infant siblings.

objectiveThe goals of this analysis were to examine birth-order differences in dietary intake between firstborn (FB) and secondborn (SB) siblings, and to determine whether a responsive parenting (RP) intervention modified birth-order effects on diet.

methodsThe Intervention Nurses Start Infants Growing on Healthy Trajectories (INSIGHT) study randomly assigned first-time mothers to an RP intervention, which included guidance on feeding, sleep, soothing, and interactive play, or control. INSIGHT mothers who delivered a second child enrolled in an observation-only study of their SB infant (SIBSIGHT). Mothers completed FFQs for both children at ages 6 (n = 97 sibling pairs) and 12 (n = 100) mo. FB compared with SB intake of food groups of interest were compared, and the moderating effect of the RP intervention on birth-order differences was tested using generalized linear mixed models.

resultsThough FBs and SBs had similar diets, more FBs than SBs consumed 100% fruit juice at both 6 (13.8 compared with 3.2%, P = 0.006) and 12 mo (46.0 compared with 32.0%, P = 0.01). SBs consumed fruit more frequently (FB 2.8 compared with SB 3.2 times/d, P = 0.01), and were more likely to consume fried potatoes (FB 38.4 compared with SB 57.6%, P = 0.0009) and processed meats (FB 43.0 compared with SB 58.0%, P = 0.02) than FBs at 12 mo. There were no differences by birth order in intake of sweets, snacks, or sugar-sweetened beverages at 12 mo. At 12 mo, RP-group SBs ate vegetables more times per day (3.2) than control SBs (2.2, P = 0.01). RP-SBs also consumed a greater variety of vegetables (10.2) than control-SBs (7.9, P = 0.01).

conclusionsBirth order is not consistently associated with healthy or unhealthy infant dietary intake. However, an RP intervention delivered to first-time mothers may benefit subsequent infants' vegetable intake. This trial was registered at clinicaltrials.gov as NCT01167270.

Indexed as

Birth OrderDiet, HealthyMother-Child RelationsParentingAdultChild, PreschoolEducation, NonprofessionalFemaleHumansInfantInfant FoodMaleNursesVegetablesbirth orderdietary intakeinfantresponsive parentingsiblings

Identifiers

PMID32412629
PMCPMC7398778
OpenAlexW3026524388

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.