Trial reportJournal of medical Internet research2020
A Mobile App Lifestyle Intervention to Improve Healthy Nutrition in Women Before and During Early Pregnancy: Single-Center Randomized Controlled Trial.
Trial report in Journal of medical Internet research, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 49 papers, 12 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
49 citing papers in PubMed, 12 syntheses or guidelines pooled it, 78 citations in OpenAlex.
- Effectiveness of Digital Tools on Lifestyle & Health-Related Outcomes Across the Full Continuum of the Maternal Journey: A Systematic Review.Current obesity reports · 2026Pooled it
- Pre-Pregnancy Diet and/or Physical Activity Interventions for the Prevention of Gestational Diabetes Mellitus: A Systematic Review and Meta-Analysis.The Australian & New Zealand journal of obstetrics & gynaecology · 2025Pooled it
- Effectiveness of digital health in improving pregnancy quality among preconception women: A systematic review.Narra J · 2025Pooled it
- Internet-Based Interventions for Preventing Premature Birth in Preconceptional Women of Childbearing Age: Systematic Review.Journal of medical Internet research · 2025Pooled it
- Pooled it
- Association of Digital Health Interventions With Maternal and Neonatal Outcomes: Systematic Review and Meta-Analysis.Journal of medical Internet research · 2025Pooled it
- An Evaluation of Food and Nutrient Intake among Pregnant Women in The Netherlands: A Systematic Review.Nutrients · 2023Pooled it
- Addressing Preconception Behavior Change Through Mobile Phone Apps: Systematic Review and Meta-analysis.Journal of medical Internet research · 2023Pooled it
- Usage of Mobile Applications or Mobile Health Technology to Improve Diet Quality in Adults.Nutrients · 2022Pooled it
- Facilitators and Barriers to the Adoption of Telemedicine During the First Year of COVID-19: Systematic Review.Journal of medical Internet research · 2022Pooled it
- Preconceptional maternal weight loss and hypertensive disorders in pregnancy: a systematic review and meta-analysis.European journal of clinical nutrition · 2021Pooled it
- Preconception lifestyle advice for people with infertility.The Cochrane database of systematic reviews · 2021Pooled it
- Further development and (cost-)effectiveness of the Smarter Pregnancy lifestyle program tailored for pregnant women with obesity (HYGEIA trial).BMC pregnancy and childbirth · 2026Trial
- Efficacy of a Personalized mHealth App in Improving Micronutrient Supplement Use Among Pregnant Women in Karachi, Pakistan: Parallel-Group Randomized Controlled Trial.Journal of medical Internet research · 2025Trial
- The effect of a locally tailored intervention on the uptake of preconception care in the Netherlands: a stepped-wedge cluster randomized trial (APROPOS-II study).BMC public health · 2022Trial
- A Remote Nutritional Intervention to Change the Dietary Habits of Patients Undergoing Ablation of Atrial Fibrillation: Randomized Controlled Trial.Journal of medical Internet research · 2020Trial
- Efficacy of a Mobile Health App in Promoting Breastfeeding and Young Child Feeding Practices in Pakistan: Protocol for a Randomized Controlled Trial.JMIR research protocols · 2026Article
- Effect of a digital dietary intervention on diet quality in young adults in Norway - The PREPARED randomised controlled trial.BMC nutrition · 2026Article
- Community-based interventions to improve adolescent nutrition: a scoping review.BMC public health · 2025Article
- Young adults' experience with using a web based digital resource to promote healthy preconception diet.BMC nutrition · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundUnhealthy nutrition contributes to the worldwide rising prevalence of noncommunicable diseases. As most adverse reproductive outcomes originate during the periconception period, effective interventions targeting this period are needed. Therefore, we developed the lifestyle intervention Smarter Pregnancy to empower women to adapt a healthy diet prior to conception and during early pregnancy and performed a randomized controlled trial.
objectiveThe objectives of this trial were to investigate compliance and effectiveness in women using the Smarter Pregnancy program.
methodsWomen aged between 18 and 45 years who were contemplating pregnancy or <13 weeks pregnant and their male partners living in the urban area of Rotterdam, the Netherlands, were eligible for participation. After baseline screening, the intervention group received personal online coaching based on identified inadequate intakes of vegetables, fruits, and folic acid supplements. The sum of these risk factors was used as a dietary risk score (DRS), ranging from 0 (healthy) to 9 (unhealthy). The control group did not receive coaching. We applied an intention-to-treat principle and used a multivariable linear regression model to evaluate the change in DRS after 24 weeks. Compliance was defined as the percentage of women who completed the screening questionnaire at 24 weeks.
resultsOf women recruited, 81.2% (177/218) completed the program (intervention: 91/218, 83.5%; control: 86/218, 78.9%; P=.95). After 24 weeks, the reduction in DRS of women in the intervention group was significantly larger than in the control group (β=.75, 95% CI 0.18-1.34). This reduction was mainly due to increased vegetable intake (β=.55, 95% CI 0.25-0.86).
conclusionsThe high compliance and the larger improvements in nutritional behaviors, especially vegetable intake, in women in the intervention group emphasizes the effectiveness of empowering women by using the lifestyle change intervention Smarter Pregnancy.
trial registrationNetherlands Trial Register: NL3927; https://www.trialregister.nl/trial/3927. INTERNATIONAL REGISTERED REPORT IDENTIFIER (IRRID): RR2-10.1186/s12884-017-1228-5.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.