ArticleJournal of the American Chemical Society2020
Nickel-Catalyzed Cross-Electrophile Coupling of Aryl Chlorides with Primary Alkyl Chlorides.
Article in Journal of the American Chemical Society, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 46 papers.
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Who cites it
46 citing papers in PubMed.
- The Preparation and Systematic Evaluation of Ligated Ni(II) Pre-Catalysts (NiPC) in Common Single Electron Cross-Coupling Reactions.ACS medicinal chemistry letters · 2026Article
- DiploPhos: A Hemilabile Bisphosphine for Sterically Hindered Ni-Catalyzed Suzuki-Miyaura Couplings.ACS catalysis · 2026Article
- Nickel-Catalyzed Radical-Radical Cross-Coupling Reactions.Chemistry (Weinheim an der Bergstrasse, Germany) · 2026Review
- Ring-opening decarbonylative C(spChemical science · 2026Article
- Article
- LMCT-driven electron relay unlocks alcohols as tunable reductants for nickel-catalyzed cross-electrophilic couplings.Nature communications · 2025Article
- Ni/Ti Dual Catalyzed Cross-Electrophile Coupling Between Unactivated Alkyl Chlorides and Aryl Halides.ACS catalysis · 2025Article
- Aryl Acid-Alcohol Cross-Coupling: C(spJournal of the American Chemical Society · 2025Article
- Translation of Nickel-Catalyzed C(spOrganic letters · 2025Article
- Easily Accessible and Solution-Stable Ni(0) Precatalysts for High-Throughput Experimentation.Chemistry (Weinheim an der Bergstrasse, Germany) · 2025Article
- One-Pot Chlorination and Cross-Electrophile Coupling of Alcohols with Aryl Chlorides.Organic letters · 2025Article
- Nickel-Catalyzed Cross-Electrophile Coupling of Aryl Triflates with Alkyl Halides: Mechanism-Informed Design of More General Conditions.Journal of the American Chemical Society · 2025Article
- Cross-Electrophile Coupling: Principles, Methods, and Applications in Synthesis.Chemical reviews · 2024Review
- Regiodivergent Radical-Relay Alkene Dicarbofunctionalization.Journal of the American Chemical Society · 2024Article
- Electrosynthesis of iminophosphoranes and applications in nickel catalysis.Chemical science · 2024Article
- Nickel-catalyzed γ-alkylation of cyclopropyl ketones with unactivated primary alkyl chlorides: balancing reactivity and selectivityRSC advances · 2024Article
- Ni-catalyzed enantioconvergent deoxygenative reductive cross-coupling of unactivated alkyl alcohols and aryl bromides.Nature communications · 2024Article
- Ni-Catalyzed Stereoconvergent Reductive Dimerization of Bromocyclobutenes.Organic letters · 2024Article
- Iron-Catalyzed Enantioselective Multicomponent Cross-Couplings of α-Boryl Radicals.Organic letters · 2023Article
- Electrochemical halogen-atom transfer alkylation via α-aminoalkyl radical activation of alkyl iodides.Nature communications · 2023Article
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4 authors.
Funding
Abstract
Alkyl chlorides and aryl chlorides are among the most abundant and stable carbon electrophiles. Although their coupling with carbon nucleophiles is well developed, the cross-electrophile coupling of aryl chlorides with alkyl chlorides has remained a challenge. We report here the first general approach to this transformation. The key to productive, selective cross-coupling is the use of a small amount of iodide or bromide along with a recently reported ligand, pyridine-2,6-bis(
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