Evidence map›Paper›PMID 32412088›Full record

SynthesisActa neurologica Scandinavica2020

Neurological Manifestations of COVID-19: A systematic review and current update.

Abigail Whittaker, Matthew Anson, Amer Harky

Abstract readSystematic Review
PubMed Full text at PMC Publisher
In one paragraph

Synthesis in Acta neurologica Scandinavica, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 218 papers, 19 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
218citing papers in PubMed, 19 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

218 citing papers in PubMed, 19 syntheses or guidelines pooled it.

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158 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Abigail WhittakerDepartment of Medicine, St George's University of London, London, UK.
Matthew AnsonDepartment of Medicine, St George's University of London, London, UK.
Amer HarkyDepartment of Cardiothoracic Surgery, Liverpool Heart and Chest, Liverpool, UK.ORCID https://orcid.org/0000-0001-5507-5841

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The novel coronavirus, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), was first identified in December of 2019 in the city of Wuhan, China. Since the outbreak, various reports detail its symptoms and outcomes, primarily focusing on respiratory complications. However, reports are emerging of the virus' effects systemically, including that of the nervous system. A review of all current published literature was conducted, and we report that headache and anosmia were common neurological manifestations of SARS-CoV-2. Less common symptoms include seizure, stroke and isolated cases of Guillain-Barre syndrome. Further research is now warranted to precisely determine the relationship between those patients developing neurological sequelae, their clinical state and any subsequent morbidity and mortality.

Indexed as

Coronavirus InfectionsNervous System DiseasesPandemicsPneumonia, ViralBetacoronavirusChinaCoronavirusCOVID-19Disease OutbreaksHumansSARS-CoV-2Severe acute respiratory syndrome-related coronavirusCOVID-19nervous systemneurologySARS-CoV-2

Identifiers

PMID32412088
PMCPMC7273036

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.