ArticleBMJ open ophthalmology2020
Progression to blindness in 20 years among patients with glaucomatous visual field loss in a tertiary hospital in the Philippines.
Article in BMJ open ophthalmology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed, 0 citations in OpenAlex.
- Fast Progressors in Primary Open-Angle Glaucoma: A 5-Year Visual Field Index-Based Classification in a Real-World Cohort.Ophthalmology and therapy · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveTo determine visual field (VF) rates of change among patients with glaucomatous VF loss and proportion of those becoming blind based on residual life expectancy and factors associated with fast progression. METHODS AND ANALYSIS: This was a retrospective study of the VFs of patients with glaucomatous VF defects in at least one eye. Baseline and final VFs were reviewed. Rates of VF change (decibels (dB)/year) for each eye, together with the residual life expectancy based on age and sex, were used to predict mean deviation/defect (MD) at the end of expected lifetime. Blindness was defined if computed MD was 22 dB (Octopus) or -22 dB (Humphrey) or worse in the better eye. Factors associated with fast progression (>1 dB/year for Octopus or <-1 dB/year for Humphrey) and blindness were determined.
resultsThere were 1016 eyes of 583 patients eligible. There was decline in VF MD/year in 613/1016 (60.3%), 95% CI (57.3% to 63.3%) of eyes; however, only 98/1016 (9.7%), 95% CI (7.9% to 11.5%) of eyes showed fast progression. Among patients with bilateral VFs, 43/433 (9.9%), 95% CI (7.1 to 12.8) of eyes were predicted to progress to blindness. In multivariate analysis, factors associated with fast progression were baseline MD (p<0.001) and male sex (p=0.041). Factors associated with blindness were age <60 years (p=0.003), baseline MD (p=0.022), bilateral glaucomatous VF defects (p=<0.001) and fast progression (p<0.001).
conclusionPatients reaching blindness in a routine clinical setting was 10%. Because of association of age and baseline MD on blindness, early disease detection is important. VF progression rates and residual life expectancy must be incorporated in glaucoma care.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.