Evidence map›Paper›PMID 32411764›Full record

ArticleAnnals of translational medicine2020

The neutrophil-to-lymphocyte ratio is a predictive factor for the survival of patients with hepatocellular carcinoma undergoing transarterial chemoembolization.

Chengguo Wang, Mengmeng Wang, Xiangnan Zhang, Shoujie Zhao, Jie Hu, Guohong Han, Lei Liu

Abstract read
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Article in Annals of translational medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.

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23citing papers in PubMed
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1 · What the graph read from it

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

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3 · Its place in the literature

Who cites it

23 citing papers in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

7 authors.

Chengguo WangDepartment of General Surgery, Tangdu Hospital, Fourth Military Medical University, Xi'an 710038, China.
Mengmeng WangDepartment of Drug and Equipment, Aeromedicine Identification and Training Centre of Air Force, Xi'an 710069, China.
Xiangnan ZhangDivision of Scientific Research, Tangdu Hospital, Fourth Military Medical University, Xi'an 710038, China.
Shoujie ZhaoDepartment of General Surgery, Tangdu Hospital, Fourth Military Medical University, Xi'an 710038, China.
Jie HuDepartment of Clinical laboratory, Tangdu Hospital, Fourth Military Medical University, Xi'an 710038, China.
Guohong HanDepartment of Liver Disease and Digestive Interventional Radiology, Xijing Hospital of Digestive Diseases, Fourth Military Medical University, Xi'an 710032, China.
Lei LiuDepartment of Gastroenterology, Tangdu Hospital, Fourth Military Medical University, Xi'an 710038, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundNeutrophil-to-lymphocyte ratio (NLR) is considered as a prognostic predictor of hepatocellular carcinoma (HCC). However, its prognostic ability is still controversial. This study aimed to evaluate the prognostic value of NLR changes in HCC patients undergoing transarterial chemoembolization (TACE).

methodsThe patients who were newly diagnosed with HCC and treated with TACE in our center from July 2010 to December 2014 were enrolled in the study. The factors, including NLR, were recorded at baseline and three days and one month after TACE.

resultsA total of 380 consecutive patients were studied retrospectively. The median NLR values at baseline, 3 days and 1 month after TACE (2.4, 6.3 and 2.4 respectively), were used as the cut-off value for patient stratification. Compared with the patients in low NLR group, those with high NLR had a larger tumor size. For baseline measurement, the low NLR group showed improved overall survival (OS) compared with the high group (median OS, 27.1

conclusionsThe dynamic changes of baseline NLR are significantly associated with OS in HCC patients treated with TACE, and as a result patient selection and prognostic prediction may be refined.

Indexed as

Hepatocellular carcinoma (HCC)neutrophil-to-lymphocyte ratio (NLR)overall survival (OS)prognosistransarterial chemoembolization (TACE)

Identifiers

PMID32411764
PMCPMC7214899

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.