Evidence map›Paper›PMID 32411691›Full record

ArticleFrontiers in bioengineering and biotechnology2020

Bioprinting Cell- and Spheroid-Laden Protein-Engineered Hydrogels as Tissue-on-Chip Platforms.

Daniela F Duarte Campos, Christopher D Lindsay, Julien G Roth, Bauer L LeSavage, Alexis J Seymour, Brad A Krajina, Ricardo Ribeiro, Pedro F Costa, Andreas Blaeser, Sarah C Heilshorn

Abstract read
In one paragraph

Article in Frontiers in bioengineering and biotechnology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers.

0numbers the graph read from it
0cells of the map it votes in
31citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

31 citing papers in PubMed.

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  8. Contribution of the ELRs to the development of advancedFrontiers in bioengineering and biotechnology · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Daniela F Duarte CamposDepartment of Materials Science & Engineering, Stanford University, Stanford, CA, United States.
Christopher D LindsayDepartment of Materials Science & Engineering, Stanford University, Stanford, CA, United States.
Julien G RothStanford Medical School, Institute for Stem Cell Biology and Regenerative Medicine, Stanford University, Stanford, CA, United States.
Bauer L LeSavageDepartment of Bioengineering, Stanford University, Stanford, CA, United States.
Alexis J SeymourDepartment of Bioengineering, Stanford University, Stanford, CA, United States.
Brad A KrajinaDepartment of Materials Science & Engineering, Stanford University, Stanford, CA, United States.
Ricardo RibeiroBiofabics, Porto, Portugal.
Pedro F CostaBiofabics, Porto, Portugal.
Andreas BlaeserInstitute for BioMedical Printing Technology, Technical University of Darmstadt, Darmstadt, Germany.
Sarah C HeilshornDepartment of Materials Science & Engineering, Stanford University, Stanford, CA, United States.

Funding

Engineered matrix microarrays to enhance the regenerative potential of iPSC-derived endothelial cellsR01HL142718 · NHLBI · STANFORD UNIVERSITY · PI HEILSHORN, SARAH C, HUANG, NGAN F. · 2018 to 2021
$1.6M
Injectable Hydrogels to Protect Transplanted Cells from HypoxiaR01EB027666 · NIBIB · STANFORD UNIVERSITY · PI HEILSHORN, SARAH C, PLANT, GILES · 2019 to 2022
$1.4M
Engineered biomaterials to modulate cell-cell signaling for the robust expansion of stem cellsR01EB027171 · NIBIB · STANFORD UNIVERSITY · PI HEILSHORN, SARAH C · 2019 to 2022
$1.4M
Combinatorial matrix-mimetic recombinant proteins as engineered nerve guidance conduitsR21NS114549 · NINDS · STANFORD UNIVERSITY · PI GEORGE, PAUL, HASTIE, TREVOR J. · 2020 to 2020
$436k
Engineered Protein Hydrogels to Modulate Adipose-derived Stromal Cell Secretome and Exosomes for Injectable Myocardial Infarction TherapyR21HL138042 · NHLBI · STANFORD UNIVERSITY · PI HEILSHORN, SARAH C · 2017 to 2018
$435k
NHLBI NIH HHS R01 HL142718NHLBI NIH HHS R21 HL138042NIBIB NIH HHS R01 EB027171NIBIB NIH HHS R01 EB027666NINDS NIH HHS R21 NS114549
6 · The paper itself

Abstract

Human tissues, both in health and disease, are exquisitely organized into complex three-dimensional architectures that inform tissue function. In biomedical research, specifically in drug discovery and personalized medicine, novel human-based three-dimensional (3D) models are needed to provide information with higher predictive value compared to state-of-the-art two-dimensional (2D) preclinical models. However, current

Indexed as

3D cell culturebioinkbioprintingprotein engineered hydrogeltissue model

Identifiers

PMID32411691
PMCPMC7198818

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.