Evidence map›Paper›PMID 32411613›Full record

ArticleFrontiers in cellular and infection microbiology2020

Predictive Metagenomic Profiling, Urine Metabolomics, and Human Marker Gene Expression as an Integrated Approach to Study Alopecia Areata.

Daniela Pinto, Francesco Maria Calabrese, Maria De Angelis, Giuseppe Celano, Giammaria Giuliani, Marco Gobbetti, Fabio Rinaldi

Open access · goldAbstract read
In one paragraph

Article in Frontiers in cellular and infection microbiology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
3.0field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 22 citations in OpenAlex.

  1. Review
  2. Review
  3. Cutaneous and Gut Dysbiosis in Alopecia Areata: A Review.JID innovations : skin science from molecules to population health · 2025
    Review
  4. Skin microbiome and dermatologic disorders.The Journal of clinical investigation · 2025
    Review
  5. Article
  6. The Gut and Skin Microbiome in Alopecia: Associations and Interventions.The Journal of clinical and aesthetic dermatology · 2023
    Review
  7. Article
  8. Review
  9. Article
  10. Article
  11. Article
  12. Journal of investigative medicine : the official publication of the American Federation for Clinical Research · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Daniela PintoHuman Microbiome Advanced Project-HMPA, Giuliani SpA, Milan, Italy.
Francesco Maria CalabreseDepartment of Soil, Plant, and Food Sciences, University of Bari Aldo Moro, Bari, Italy.
Maria De AngelisDepartment of Soil, Plant, and Food Sciences, University of Bari Aldo Moro, Bari, Italy.
Giuseppe CelanoDepartment of Soil, Plant, and Food Sciences, University of Bari Aldo Moro, Bari, Italy.
Giammaria GiulianiHuman Microbiome Advanced Project-HMPA, Giuliani SpA, Milan, Italy.
Marco GobbettiFaculty of Science and Technology, Free University of Bozen-Bolzano, Bolzano, Italy.
Fabio RinaldiHuman Microbiome Advanced Project-HMPA, Giuliani SpA, Milan, Italy.
Giuliani (Italy) · ITUniversity of Bari Aldo Moro · ITFree University of Bozen-Bolzano · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Involvement of the microbiome in many different scalp conditions has been investigated over the years. Studies on the role of the scalp microbiome in specific diseases, such as those involving hair growth alterations like non-cicatricial [androgenetic alopecia (AGA), alopecia areata (AA)] and cicatricial alopecia lichen planopilaris, are of major importance. In the present work, we highlighted the differences in microbial populations inhabiting the scalp of AA subjects and a healthy sample cohort by using an integrated approach relying on metagenomic targeted 16S sequencing analysis, urine metabolomics, and human marker gene expression. Significant differences in genera abundances (

Indexed as

Alopecia AreataBiomarkersGene ExpressionHumansMetabolomicsScalpBiomarkersalopecia areataKEGGmetabolic pathwaysmetabolomicsmetagenomic profilesmicrobiomescalp microbiomeVOCs

Identifiers

PMID32411613
PMCPMC7201066
OpenAlexW3023270747

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.