Evidence map›Paper›PMID 32411454›Full record

ArticleAIDS research and treatment2020

Does Isoniazid Preventive Therapy Provide Better Treatment Outcomes in HIV-Infected Individuals in Northern Ethiopia? A Retrospective Cohort Study.

Tesfay Mehari Atey, Helen Bitew, Solomon Weldegebreal Asgedom, Asrat Endrias, Derbew Fikadu Berhe

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in AIDS research and treatment, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 3 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Observational
  5. Review
  6. Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Tesfay Mehari AteyClinical Pharmacy Unit, School of Pharmacy, College of Health Sciences, Mekelle University, Mek'ele, Ethiopia.ORCID https://orcid.org/0000-0002-6483-2258
Helen BitewDepartment of Pharmacognosy, School of Pharmacy, College of Health Sciences, Mekelle University, Mek'ele, Ethiopia.ORCID https://orcid.org/0000-0001-7383-4960
Solomon Weldegebreal AsgedomClinical Pharmacy Unit, School of Pharmacy, College of Health Sciences, Mekelle University, Mek'ele, Ethiopia.ORCID https://orcid.org/0000-0003-0804-3307
Asrat EndriasMedical Biochemistry, Biomedical Institute, College of Health Sciences, Mekelle University, Mek'ele, Ethiopia.
Derbew Fikadu BerheDepartment of Pharmacology, School of Pharmacy, College of Health Sciences, Mekelle University, Mek'ele, Ethiopia.ORCID https://orcid.org/0000-0002-0669-9241

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesEarly antiretroviral therapy (ART), isoniazid preventive therapy (IPT), and isoniazid-rifapentine (3HP) are effective strategies for preventing tuberculosis (TB) among people living with HIV (PLHIV). The study aimed to determine the effect of IPT on the TB incidence, follow-up CD4

resultsThe follow-up CD4

conclusionThis study demonstrates the effect of IPT in reducing incidence of TB and all-cause mortality rate and improving follow-up CD4

Identifiers

PMID32411454
PMCPMC7204289

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.