Evidence map›Paper›PMID 32411434›Full record

ArticleJournal of ophthalmology2020

Multimodal Retinal Image Analysis via Deep Learning for the Diagnosis of Intermediate Dry Age-Related Macular Degeneration: A Feasibility Study.

Ehsan Vaghefi, Sophie Hill, Hannah M Kersten, David Squirrell

Abstract read
In one paragraph

Article in Journal of ophthalmology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
31citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

31 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Review
  3. Review
  4. [Research on attention-enhanced networks for subtype classification of age-related macular degeneration in optical coherence tomography].Sheng wu yi xue gong cheng xue za zhi = Journal of biomedical engineering = Shengwu yixue gongchengxue zazhi · 2025
    Article
  5. Article
  6. Review
  7. Review
  8. Article
  9. Artificial intelligence virtual assistants in primary eye care practice.Ophthalmic & physiological optics : the journal of the British College of Ophthalmic Opticians (Optometrists) · 2025
    Article
  10. Article
  11. Review
  12. Artificial intelligence in ophthalmology: opportunities, challenges, and ethical considerations.Medical hypothesis, discovery & innovation ophthalmology journal · 2025
    Review
  13. Review
  14. Article
  15. Review
  16. Multimodality Fusion Strategies in Eye Disease Diagnosis.Journal of imaging informatics in medicine · 2024
    Article
  17. RPE Curvature Can Screen for Early and Intermediate AMD.Investigative ophthalmology & visual science · 2024
    Article
  18. Article
  19. Artificial intelligence in retinal disease: clinical application, challenges, and future directions.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2023
    Review
  20. Robust AMD Stage Grading with Exclusively OCTA Modality Leveraging 3D Volume.... IEEE International Conference on Computer Vision workshops. IEEE International Conference on Computer Vision · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Ehsan VaghefiSchool of Optometry and Vision Sciences, University of Auckland, Auckland, New Zealand.ORCID https://orcid.org/0000-0002-9482-3168
Sophie HillDepartment of Ophthalmology, University of Auckland, Auckland, New Zealand.
Hannah M KerstenSchool of Optometry and Vision Sciences, University of Auckland, Auckland, New Zealand.
David SquirrellDepartment of Ophthalmology, University of Auckland, Auckland, New Zealand.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

resultsThe CNN trained using OCT alone showed a diagnostic accuracy of 94%, whilst the OCT-A trained CNN resulted in an accuracy of 91%. When multiple modalities were combined, the CNN accuracy increased to 96% in the AMD cohort.

conclusionsHere we demonstrate that superior diagnostic accuracy can be achieved when deep learning is combined with multimodal image analysis.

Identifiers

PMID32411434
PMCPMC7201607

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.