Evidence map›Paper›PMID 32411412›Full record

ReviewStroke and vascular neurology2020

Acute ischaemic stroke interventions: large vessel occlusion and beyond.

Ahmad Sweid, Batoul Hammoud, Sunidhi Ramesh, Daniella Wong, Tyler D Alexander, Joshua Harrison Weinberg, Maureen Deprince, Jaime Dougherty, Dimitri Jean-Mickael Maamari, Stavropoula Tjoumakaris and 7 more

Abstract readReview
In one paragraph

Review in Stroke and vascular neurology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
32citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

32 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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  8. Validation of the Ultimate Stroke Scale (USS): A standardized tool for automated large vessel occlusion screening.Interventional neuroradiology : journal of peritherapeutic neuroradiology, surgical procedures and related neurosciences · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors.

Ahmad SweidNeurosurgery, Thomas Jefferson University Hospital, Philadelphia, Pennsylvania, USA.
Batoul HammoudEndocrinology, Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, USA.
Sunidhi RameshSydney Kimmel Medical College, Thomas Jefferson University, Philadelphia, Pennsylvania, USA.
Daniella WongSydney Kimmel Medical College, Thomas Jefferson University, Philadelphia, Pennsylvania, USA.
Tyler D AlexanderSydney Kimmel Medical College, Thomas Jefferson University, Philadelphia, Pennsylvania, USA.
Joshua Harrison WeinbergNeurosurgery, Thomas Jefferson University Hospital, Philadelphia, Pennsylvania, USA.
Maureen DeprinceNeurosurgery, Thomas Jefferson University Hospital, Philadelphia, Pennsylvania, USA.
Jaime DoughertyNeurosurgery, Thomas Jefferson University Hospital, Philadelphia, Pennsylvania, USA.
Dimitri Jean-Mickael MaamariSchool of Medicine, American University of Beirut, Beirut, Lebanon.
Stavropoula TjoumakarisNeurosurgery, Thomas Jefferson University Hospital, Philadelphia, Pennsylvania, USA.
Hekmat ZarzourNeurosurgery, Thomas Jefferson University Hospital, Philadelphia, Pennsylvania, USA.
Michael R GoochNeurosurgery, Thomas Jefferson University Hospital, Philadelphia, Pennsylvania, USA.
Nabeel HerialNeurosurgery, Thomas Jefferson University Hospital, Philadelphia, Pennsylvania, USA.
Victor RomoAnesthesia, Thomas Jefferson University-Center City Campus, Philadelphia, Pennsylvania, USA.
David M HasanNeurosurgery, University of Iowa Hospitals and Clinics, Iowa City, Iowa, USA.
Robert H RosenwasserNeurosurgery, Thomas Jefferson University Hospital, Philadelphia, Pennsylvania, USA.
Pascal JabbourNeurosurgery, Thomas Jefferson University Hospital, Philadelphia, Pennsylvania, USA.ORCID 0000-0002-8965-2413

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Care for acute ischaemic stroke is one of the most rapidly evolving fields due to the robust outcomes achieved by mechanical thrombectomy. Large vessel occlusion (LVO) accounts for up to 38% of acute ischaemic stroke and comes with devastating outcomes for patients, families and society in the pre-intervention era. A paradigm shift and a breakthrough brought mechanical thrombectomy back into the spotlight for acute ischaemic stroke; this was because five randomised controlled trials from several countries concluded that mechanical thrombectomy for acute stroke offered overwhelming benefits. This review article will present a comprehensive overview of LVO management, techniques and devices used, and the future of stroke therapy. In addition, we review our institution experience of mechanical thrombectomy for posterior and distal circulation occlusion.

Indexed as

Endovascular ProceduresThrombectomyBrain IschemiaClinical Decision-MakingCombined Modality TherapyHumansIntracranial ThrombosisRisk AssessmentRisk FactorsStentsStrokeTreatment Outcomefunctional outcomelarge vessel occlusionmechanical thrombectomy

Identifiers

PMID32411412
PMCPMC7213503

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.