ReviewStroke and vascular neurology2020
Multimodal management of giant cerebral aneurysms: review of literature and case presentation.
Review in Stroke and vascular neurology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 2 of them syntheses that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
13 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Surgical treatment of giant intracranial aneurysms: A systematic review and single arm Meta-Analysis.Neurosurgical review · 2025Pooled it
- A Meta-analysis: Cost Comparison of Flow Diversion and Coil Embolization for Intracranial Aneurysm.Disease markers · 2022Pooled it
- Double-barrel STA-MCA bypass with endovascular parent artery occlusion for complex anterior circulation aneurysms: indications and outcomes.Acta neurochirurgica · 2026Observational
- Beyond endovascular limits: open surgical management of bilateral giant petrocavernous internal carotid artery aneurysms in a pediatric patient.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2026Article
- Extracranial-Intracranial Bypass with Reconstruction Clip Surgery Following Failed Flow Diverter Therapy for a Giant Internal Carotid Aneurysm: A Case Report.Asian journal of neurosurgery · 2025Article
- Single-Stage Microsurgical Clipping of Multiple Intracranial Aneurysms in a Patient with Cerebral Atherosclerosis: A Case Report and Review of Surgical Management.Journal of clinical medicine · 2025Article
- Large and Giant Intracranial Aneurysm: Surgical Management and Outcomes in a Tertiary Hospital.Vascular health and risk management · 2025Article
- Giant unruptured middle cerebral artery aneurysm revealed by intracranial hypertension: is a systematic decompressive hemicraniotomy mandatory?Neurosurgical review · 2024Article
- Combined open revascularization and endovascular treatment of complex intracranial aneurysms: case series.Frontiers in neurology · 2023Article
- Treatment of giant intracranial aneurysms: long-term outcomes in surgical versus endovascular management.Neurosurgical review · 2022Article
- Giant vertebral artery aneurysms presenting acutely with WFNS grade five subarachnoid haemorrhage, report of 4 cases treated with endovascular or surgical proximal parent artery occlusion achieving good functional outcome.Journal of cerebrovascular and endovascular neurosurgery · 2022Article
- Case Report: Persistent Primitive Hypoglossal Artery Accompanied by a Basilar Bifurcation Aneurysm Treated by Y-Stent-Assisted Coil Embolization.Frontiers in neurology · 2021Article
- Endovascular Treatment and Microsurgical Clipping for Intracranial Aneurysms: A Comprehensive Comparative Study.International journal of applied & basic medical researchArticle
Corrections and comments
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Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The pathophysiology of giant cerebral aneurysms renders them difficult to treat. Advances in technology have attempted to address any shortcomings associated with open surgery or endovascular therapies. Since the introduction of the flow diversion technique, the endovascular approach with flow diversion has become the first-line modality chosen to treat giant aneurysms. A subset of these giant aneurysms may persistent despite any treatment modality. Perhaps the best option for these recurrent and/or persistent giant aneurysms is to employ a multimodal approach-both surgical and endovascular-rather than any single technique to provide a curative result with favourable patient outcomes. This paper provides a review of the histopathology and treatment options for giant cerebral aneurysms. Additionally, an illustrative case is presented to highlight the unique challenges of a curative solution for giant cerebral aneurysms that persist despite initial treatment.
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Registered trials
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