Evidence map›Paper›PMID 32411397›Full record

ArticleEnvironmental epigenetics2020

Placental lncRNA expression associated with placental cadmium concentrations and birth weight.

Michael R Hussey, Amber Burt, Maya A Deyssenroth, Brian P Jackson, Ke Hao, Shouneng Peng, Jia Chen, Carmen J Marsit, Todd M Everson

Open access · goldAbstract read
In one paragraph

Article in Environmental epigenetics, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
1.4field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 24 citations in OpenAlex.

  1. Review
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  3. Article
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  6. Article
  7. Review
  8. Article
  9. LncRNAFrontiers in cell and developmental biology · 2023
    Article
  10. Review
  11. Article
  12. Review
  13. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

Michael R HusseyDepartment of Environmental Health, Rollins School of Public Health at Emory University, Atlanta, GA, USA.
Amber BurtDepartment of Environmental Health, Rollins School of Public Health at Emory University, Atlanta, GA, USA.
Maya A DeyssenrothDepartment of Environmental Medicine and Public Health, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
Brian P JacksonDepartment of Earth Sciences, Dartmouth College, Hanover, NH, USA.
Ke HaoDepartment of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
Shouneng PengDepartment of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
Jia ChenDepartment of Environmental Medicine and Public Health, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
Carmen J MarsitDepartment of Environmental Health, Rollins School of Public Health at Emory University, Atlanta, GA, USA.ORCID 0000-0003-4566-150X
Todd M EversonDepartment of Environmental Health, Rollins School of Public Health at Emory University, Atlanta, GA, USA.ORCID 0000-0003-2732-4550
Emory University · USIcahn School of Medicine at Mount Sinai · USDartmouth College · US

Funding

A prospective study of critical environmental exposures in formative early life that impact lifelong health in rural US children: the New Hampshire Birth Cohort StudyUH3OD023275 · OD · DARTMOUTH COLLEGE · PI MARGARET Rita KARAGAS, Juliette Madan · 2018 to 2026
$44.3M
Pilot Project ProgramP30ES019776 · NIEHS · EMORY UNIVERSITY · PI Carmen Joseph Marsit · 2013 to 2026
$22.6M
Project 3: Placental Biomarkers of Exposure and Outcome (Marsit)P01ES022832 · NIEHS · DARTMOUTH COLLEGE · PI MURRAY, CAROLYN J · 2013 to 2018
$4.7M
Environment, Imprinting, and NeurodevelopmentR01ES022223 · NIEHS · EMORY UNIVERSITY · PI CHEN, JIA, MARSIT, CARMEN JOSEPH · 2013 to 2017
$4.3M
Enriching the Rhode Island Child Health StudyR24ES028507 · NIEHS · EMORY UNIVERSITY · PI Carmen Joseph Marsit, LAURA R STROUD · 2017 to 2026
$2.3M
Environmental influences and function of cytosine modification in human placentaR21ES028226 · NIEHS · EMORY UNIVERSITY · PI MARSIT, CARMEN JOSEPH · 2017 to 2018
$429k
NIEHS NIH HHS P01 ES022832NIEHS NIH HHS P30 ES019776NIEHS NIH HHS R01 ES022223NIEHS NIH HHS R21 ES028226NIEHS NIH HHS R24 ES028507NIH HHS UH3 OD023275
6 · The paper itself

Abstract

Heavy metal exposures, such as cadmium, can have negative effects on infant birth weight (BW)-among other developmental outcomes-with placental dysfunction potentially playing a role in these effects. In this study, we examined how differential placental expression of long non-coding RNAs (lncRNAs) may be associated with cadmium levels in placenta and whether differences in the expression of those lncRNAs were associated with fetal growth. In the Rhode Island Child Health Study, we used data from Illumina HiSeq whole transcriptome RNA sequencing (

Indexed as

cadmiumexpressionfetal growthlincRNAprenatal

Identifiers

PMID32411397
PMCPMC7211362
OpenAlexW3020993406

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.